Long-term follow-up after limb salvage in skeletally immature children with a primary malignant tumor of the distal end of the femur

The Journal of Bone and Joint Surgery. American Volume
Hiroyuki FutaniTakafumi Ueda

Abstract

Skeletally immature children with a primary malignant tumor in the distal end of the femur are candidates for limb-salvage surgery; however, functional impairment due to subsequent limb-length discrepancy must be considered. Our aim was to evaluate the long-term clinical outcome of limb salvage in patients with a sarcoma of the distal end of the femur who were eleven years old or less, focusing on limb-length discrepancy and complications. The cases of forty children were retrospectively reviewed in a multicenter study based on the responses to a questionnaire. Twenty-eight patients had had endoprosthetic reconstruction, and twelve had had biological reconstruction. Functional evaluation was based on the Musculoskeletal Tumor Society scoring system, with numerical values from 0 to 5 points assigned for each of the following six categories: pain, function, emotional acceptance, use of supports, walking ability, and gait. These values were added, and the functional score was presented as a percentage of the maximum possible score. Limb-length discrepancy was measured with orthoroentgenograms. Complications and their treatment were analyzed. Patient survival and the survival of the reconstructions were analyzed with use of the Kap...Continue Reading

Citations

Aug 10, 2006·International Orthopaedics·D OrlicM Bergovec
May 18, 2012·Archives of Orthopaedic and Trauma Surgery·Irfan QadirNaveed Baloch
Mar 17, 2011·Journal of Pediatric Orthopedics. Part B·Ajay Puri, Ashish Gulia
Mar 14, 2013·Journal of Pediatric Orthopedics·Pietro RuggieriMario Mercuri
Feb 24, 2012·AJR. American Journal of Roentgenology·Jan FritzLaura M Fayad
Mar 23, 2011·Vojnosanitetski pregled. Military-medical and pharmaceutical review·Radoslav BarjaktarovićDragan Radoicié
Aug 9, 2012·The Journal of Pediatrics·Melissa SheikoErnest U Conrad
Oct 4, 2011·Journal of Children's Orthopaedics·Amit DotanIsaac Meller
May 31, 2011·Pain Management Nursing : Official Journal of the American Society of Pain Management Nurses·Doralina L AnghelescuGisele M Hankins
May 17, 2012·Orthopedics·Andreas F MavrogenisPanayiotis J Papagelopoulos
Mar 19, 2009·Orthopedics·Steven GitelisSusan Shott
May 6, 2008·Revue de chirurgie orthopédique et réparatrice de l'appareil moteur·M ThaunatJ Dubousset
Mar 11, 2015·Pediatric Blood & Cancer·Sabrina Jeane Prates EleutérioAntonio Sergio Petrilli
Jun 20, 2015·Case Reports in Orthopedics·Eric R HendersonG Douglas Letson
Mar 10, 2009·The Knee·Christopher P CartyPeter Steadman
Nov 20, 2015·The Journal of Bone and Joint Surgery. American Volume·Annie ArteauPatrick P Lin
Apr 27, 2010·Clinical Orthopaedics and Related Research·Raffi S AvedianTerrance D Peabody
Jul 16, 2010·Clinical Orthopaedics and Related Research·Eric R HendersonG Douglas Letson
Mar 13, 2018·Clinical Orthopaedics and Related Research·Luis A Aponte-TinaoGerman L Farfalli
Oct 12, 2014·Journal of Pediatric Orthopedics. Part B·Rebecca TateJuliet Hale
Jun 4, 2008·The Journal of Bone and Joint Surgery. American Volume·L M JeysA Abudu
Mar 4, 2011·The Journal of Bone and Joint Surgery. American Volume·Eric R HendersonG Douglas Letson
Jan 1, 2009·Revista Brasileira De Ortopedia·Valter PennaRicardo Gehrke Becker

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.