Long-term follow-up after multiple plastic stenting for refractory pancreatic duct strictures in chronic pancreatitis

Endoscopy
Andrea TringaliGuido Costamagna

Abstract

Dominant pancreatic duct strictures in chronic pancreatitis are often managed by endoscopic placement of a single plastic stent. Insertion of multiple plastic stents (MPS) has been proven to be effective in managing refractory strictures, but data are still limited. The aim of this study was to investigate the efficacy and long-term results of MPS to dilate pancreatic duct strictures in chronic pancreatitis. 48 patients (34 men; mean age 44 years) with chronic pancreatitis and a single pancreatic stent through a refractory stricture in the pancreatic head underwent the following protocol: 1) removal of the single pancreatic stent; 2) balloon dilation of the stricture; 3) insertion of the maximum number of stents; 4) stent removal after 6 - 12 months. The median number of pancreatic plastic stents placed was 3 (diameter 7 - 11.5 Fr, length 3 - 7 cm). Five patients (10.4 %) had persistent strictures after MPS removal. During a mean follow-up of 9.5 years (0.3 - 15.5 years) after stent removal, 74.4 % (32/43) of the patients were asymptomatic, and 25.6 % (11/43) experienced pancreatitis recurrence or pancreatic type pain after a mean time of 26.4 months (8/43, 18.6 % underwent plug extraction without evidence of stricture recurren...Continue Reading

Citations

Mar 21, 2020·Scandinavian Journal of Surgery : SJS : Official Organ for the Finnish Surgical Society and the Scandinavian Surgical Society·R ValenteJ-M Löhr
Mar 21, 2020·Scandinavian Journal of Surgery : SJS : Official Organ for the Finnish Surgical Society and the Scandinavian Surgical Society·M UddA Kokkola
Jun 9, 2020·Expert Review of Gastroenterology & Hepatology·Theodor VoiosuGuido Costamagna
Dec 4, 2020·Revista Española De Enfermedades Digestivas : Organo Oficial De La Sociedad Española De Patología Digestiva·Juan J Vila, Federico Bolado
Mar 10, 2021·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Zaheer Nabi, Sundeep Lakhtakia
May 5, 2021·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·Aijaz Ahmed SofiJohn Vargo
Jun 29, 2021·Disease-a-month : DM·Rupinder MannShreyas Saligram
Aug 19, 2021·Clinical Journal of Gastroenterology·Vaneet JearthSridhar Sundaram
Mar 5, 2021·Clinical Endoscopy·Sridhar SundaramAkash Shukla

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