Long-term follow-up in adults with coeliac disease: Predictors and effect on health outcomes

Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
Henna PekkiKalle Kurppa

Abstract

Guidelines recommend regular follow-up in coeliac disease, but effect of this on long-term outcomes remains unclear. To evaluate predictors and significance of long-term follow-up. 677 previously diagnosed coeliac patients were recruited for a nationwide health survey. Medical data were gathered through interviews and patient records. Current symptoms and quality of life were assessed by validated questionnaires and blood samples were drawn for serology. All variables were compared between patients with and without long-term (>2 years) follow-up. 15% had long-term follow-up, median duration 10 years. Predictors (p < 0.05) for the follow-up were immunological (35% vs. 24%) and circulatory (20% vs. 12%) comorbidities, whereas it was less common in subjects with musculoskeletal (23% vs. 34%) comorbidity and those not belonging to any at-risk group (16% vs. 27%). Patients with or without follow-up had comparable age, adherence and ability to manage a gluten-free diet and frequency of seropositivity. Also questionnaire scores paralleled, but those without follow-up reported more overall symptoms (16% vs. 26%). Most patients wished for follow-up. Only a minority of patients had regular follow-up. However, patients with and without th...Continue Reading

Citations

Feb 24, 2021·Scandinavian Journal of Gastroenterology·Jesper LexnerKlas Sjöberg
Jan 7, 2021·European Journal of Gastroenterology & Hepatology·Petra RiznikJernej Dolinsek

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