PMID: 2208026Oct 15, 1990Paper

Long-term follow-up of 24 patients undergoing radical resection for ampullary carcinoma, 1953 to 1988

Cancer
W P ShutzeJ S Aldrete

Abstract

Potentially curative radical pancreaticoduodenectomy for ampullary adenocarcinoma was performed in 24 patients over a 35-year period. The overall operative mortality was 12.5%. Actuarial survival rate at 5 years was 61% +/- 13.4 standard error of the mean (SEM) and subsequently remained unchanged. In the same time period, 21 patients underwent potentially curative radical pancreaticoduodenectomy for periampullary tumors of pancreatic origin. Similar analysis showed an overall operative mortality of 23.8% and a survival rate at 5 years of 27% +/- 12.5 SEM. The results of radical pancreaticoduodenectomy for ampullary carcinoma in the most recent years (1976 to 1988) were compared with those of former years (1953 to 1975). There were no statistically significant differences in the 5-year survival rate; however, the operative mortality decreased from 25% in the former period to 6.3% in the recent period. Survival was dependent on nodal status. The 5-year survival rate was 78% +/- 11.5 SEM in the absence of nodal metastasis versus 50% +/- 25 SEM in the presence of regional nodal metastasis. These findings support the concept that radical pancreaticoduodenectomy offers a realistic probability for cure in a selected group of patients ...Continue Reading

References

Feb 1, 1976·American Journal of Surgery·L WiseL P Dehner
Apr 1, 1977·Archives of Surgery·O E AkwariA H Baggenstoss
Feb 1, 1979·Annals of Surgery·J F Forrest, W P Longmire
Dec 1, 1977·Annals of Surgery·T CoutsoftidesH R Shibata
Jun 1, 1978·American Journal of Surgery·W SchlippertJ Christensen
May 1, 1975·Annals of Surgery·K W WarrenM Relihan
Nov 1, 1987·Annals of Surgery·D H HayesJ C Bowen
Jan 1, 1986·American Journal of Surgery·P A GraceW P Longmire
Jan 1, 1985·American Journal of Surgery·B A JonesM Girotti
Feb 1, 1982·American Journal of Surgery·R J PiorkowskiJ J Terz
Mar 1, 1982·Annals of Surgery·F P HerterC Antinori
Feb 1, 1982·Annals of Surgery·D B WalshS M Lindenauer
May 1, 1982·Annals of Surgery·J R CohenP Dineen
Dec 1, 1981·The Ceylon Medical Journal·G S Balasubramaniam, E A Andree
Oct 1, 1935·Annals of Surgery·A O WhippleC R Mullins

❮ Previous
Next ❯

Citations

Jul 1, 1992·Journal of Surgical Oncology·K Yamaguchi, K Nishihara
Dec 2, 2006·Journal of Hepato-biliary-pancreatic Surgery·Toshiyuki MoriyaAkira Fuse
Jun 23, 2000·International Journal of Radiation Oncology, Biology, Physics·J H LeeE F Rosato
Feb 13, 2001·Critical Reviews in Oncology/hematology·M ConioR Dumas
Nov 1, 1996·Annals of Surgery·G D BranumW C Meyers
Oct 1, 1993·Surgery, Gynecology & Obstetrics·Y L MatoryM Brennan
Mar 10, 2006·World Journal of Surgical Oncology·Haralampos DemetriadesDimitrios Betsis
Oct 3, 1999·The British Journal of Radiology·H KuboH Nawata
Nov 15, 1997·The British Journal of Surgery·T NakaiM Yasutomi
Mar 12, 2008·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Laurence ChichePhilippe Segol
Apr 28, 2009·International Journal of Radiation Oncology, Biology, Physics·Kyubo KimSung W Ha
Nov 14, 2006·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·J SakataK Hatakeyama
Apr 1, 1997·Journal of Pediatric Surgery·F AndiranA Hiçsönmez
Jun 1, 2006·World Journal of Surgery·Eiko SakataKatsuyoshi Hatakeyama
May 1, 1994·The British Journal of Surgery·C SpertiS Pedrazzoli
Mar 27, 2001·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·S N AgoffR C Haggitt
Jan 6, 2001·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·M TakashimaM Tsuneyoshi
Dec 9, 2014·Hospital Practice·Sarah R Ahmad, Douglas G Adler
Apr 1, 1993·The Australian and New Zealand Journal of Surgery·K YamaguchiM Tamaka

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.