Long-term follow-up of hepatic adenoma and adenomatosis: analysis of size change on imaging with histopathological correlation

Clinical Radiology
N ShaoI R Kamel

Abstract

To analyse the change in size on follow-up of hepatic adenomas (HAs) and adenomatosis, and to investigate the relationship of imaging features with size change. The study included 44 patients (142 lesions) who underwent magnetic resonance imaging (MRI) or computed tomography (CT) for diagnosis and follow-up of HA. The imaging features and percentage change in maximum tumour dimension were observed over a follow-up duration of up to 139 months. With an average follow-up of 43 months, 37% lesions decreased in size, 58% were stable, 4% increased; one lesion regressed completely. Adenomas were stratified into size groups (<3, 3-5, and ≥5 cm). Size change among the three groups was similar (p>0.05). Percent size change was different for lesions followed for ≤12 months (-7.2%) compared with lesions followed for 13-60 months (-20.5%), and those followed for ≥60 months (-23.5%; p<0.05); there was no difference between lesions followed for 13-60 months and ≥60 months (p=0.523). Baseline size and percent size change was similar between the hepatocyte nuclear factor 1α-inactivated HA (HA-H) and inflammatory HA (HA-I) subtype (p>0.05). Most adenomas were either stable or regressed on follow-up. Size change was independent of baseline size....Continue Reading

Citations

Mar 18, 2020·Radiology·Federica VernuccioValérie Vilgrain
May 21, 2020·European Journal of Gastroenterology & Hepatology·Beverly T RodriguesAmanda J Nicoll
Aug 16, 2018·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Diamantis I TsilimigrasTimothy M Pawlik
Oct 19, 2019·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Pegah KhoshpouriIhab R Kamel
Dec 3, 2020·British Journal of Hospital Medicine·Anitha James
Jul 6, 2020·Clinics in Liver Disease·Lauren Myers, Joseph Ahn

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Liver Cell Adenoma or hepatic adenoma is a rare benign tumor. It is associated with birth control use or pregnancy. Discover the latest research on Liver Cell Adenoma here.

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