Long term follow-up of lenticular autofluorescence and transmittance in healthy volunteers

Experimental Eye Research
J A van BestJ E Keunen

Abstract

This study was undertaken to assess long term changes in the lenticular autofluorescence and transmittance of healthy volunteers. Both eyes of 15 healthy volunteers aged 8 to 62 years were examined by slit-lamp examination and fluorophotometric measurements of lenticular autofluorescence (lambdaexc=415 nm-490 nm, lambdaem= 510 nm-550 nm) and transmittance (lambda=415 nm-550 nm) in 1983 and 1996. The changes in lenticular autofluorescence and transmittance between 1983 and 1996 were determined and compared with those calculated on the basis of age-dependence curves of a group of 56 healthy volunteers measured in 1983. These curves were obtained by approximation of the values of the 56 healthy volunteers by a linear, polynomial or exponential function of age, respectively. A mean yearly increase of lenticular autofluorescence of 8.69 ng . equivalent fluorescein . ml-1 . year-1 was observed in the 15 volunteers between 1983 and 1996 and this increase was significantly larger than that calculated on the basis of the three age-dependence curves in 1983 (6.36, 6.47 and 6.53 ng . equivalent fluorescein . ml-1 . year-1, P=0.0026, 0.0037 and 0.0044, respectively). The transmittance showed a mean yearly decrease of 0.508% . year-1 which ...Continue Reading

References

Jan 1, 1992·Experimental Eye Research·P M BoetsJ A van Best
Jan 1, 1989·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·E van WirdumJ Oosterhuis
Jan 1, 1988·Ophthalmic Research·E van WirdumA Marques
Jan 1, 1988·The Journal of Physiology·R A Weale
Sep 22, 1996·Proceedings. Biological Sciences·R A Weale
Jul 1, 1996·Journal of Biomedical Optics·J A Van Best, E V Kuppens
Jul 1, 1996·Journal of Biomedical Optics·R A Weale

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Citations

Aug 20, 2004·The British Journal of Ophthalmology·L KesselM Larsen
Oct 23, 2013·The Journal of Physiology·Seong Jae KimPhyllis C Zee
Apr 16, 2010·Medical Hypotheses·Glyn Walsh, E Ian Pearce
Mar 16, 2007·Experimental Eye Research·Xianmin LuoSteven Bassnett
Jul 23, 2005·Annals of the New York Academy of Sciences·Robbert MeerwaldtAndries Smit
Jan 24, 2004·Photodermatology, Photoimmunology & Photomedicine·Jane Sandby-MøllerHans Christian Wulf
Apr 8, 2011·Acta Ophthalmologica·Inger Christine MunchMichael Larsen
Jan 13, 2004·Journal of Biomedical Optics·Luigi Rovati, Franco Docchio
Mar 9, 2007·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·M NorvalJ C van der Leun
May 6, 2016·Journal of Diabetes·Ana M Calvo-MarotoAlejandro Cerviño

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