Long-term follow-up of patients after endoscopic sphincterotomy for choledocholithiasis, and risk factors for recurrence

Endoscopy
G CostamagnaV Perri

Abstract

There have been growing concerns about the long-term sequelae of endoscopic sphincterotomy (ES). The aims of the study were to evaluate the long-term clinical outcome of ES for choledocholithiasis and to identify the predictors of recurrence. A total of 529 patients (233 men, 296 women; mean age 63, range 9 - 88) who underwent successful ES for choledocholithiasis were evaluated. Follow-up data were obtained retrospectively. Statistical analyses were carried out for 334 patients who had a follow-up of at least 5 years or had recurrence. Immediate complications occurred in 37 patients (7 %). Follow-up data were available in 458 patients (86.6 %), of whom 280 (61.1 %) were asymptomatic, 127 (27.7 %) died from unrelated causes without recurrence, and 51 (11.1 %) had biliary symptoms and/or choledocholithiasis recurrence. Most recurrences (65 %) occurred more than 2 years following ES and were observed on multiple occasions in 13 patients (2.8 %). A bile duct diameter of 22 mm or greater was found to predict recurrence. Of 190 patients with an intact gallbladder, 11 (5.8 %) developed acute cholecystitis necessitating emergency cholecystectomy; all of these had previously documented gallstones. Endoscopic sphincterotomy for choledoc...Continue Reading

Citations

Jan 26, 2007·Journal of Hepato-biliary-pancreatic Surgery·Masato NaginoAvinash Supe
Jul 26, 2011·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Shyam VaradarajuluC Mel Wilcox
Jun 12, 2004·Current Gastroenterology Reports·Meinhard Classen, Peter Born
May 9, 2008·Current Gastroenterology Reports·Naveen GuptaFiras Al-Kawas
Sep 21, 2002·Lancet·Alfred Cuschieri
Feb 11, 2005·Current Opinion in Gastroenterology·Michelle C Beilstein, Michael L Kochman
Jun 17, 2008·Journal of Gastroenterology and Hepatology·Shin TsuchiyaOsamu Yokosuka
Aug 26, 2009·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Masayuki KitanoMasatoshi Kudo
Aug 21, 2009·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Masanobu KageokaKentarou Ikeya
May 8, 2010·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Tatsuya FujimotoOsamu Yokosuka
Feb 1, 2013·PloS One·Pavel StrnadHasan Kulaksiz
Mar 1, 2012·World Journal of Gastroenterology : WJG·John KalaitzisAndreas Polydorou
Jul 11, 2014·World Journal of Gastroenterology : WJG·Feng LiuBin Song
Jul 3, 2008·Digestive Diseases and Sciences·Thomas KowalskiDavid Loren
Apr 3, 2013·Digestive Diseases and Sciences·Sang Eon JangYoung Hoon Kim
Oct 9, 2009·Scandinavian Journal of Gastroenterology·Kjell-Arne UngAntal Bajor
May 14, 2004·Asian Journal of Surgery·Terrence H Liu, Claude H Organ
Sep 29, 2011·Gastrointestinal Endoscopy·John T MapleJason A Dominitz
Aug 13, 2010·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Domenico AlvaroUNKNOWN Italian Association of Oncological Radiotherapy (AIRO)
Jan 26, 2010·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Manuela GattoDomenico Alvaro
Sep 16, 2008·Best Practice & Research. Clinical Gastroenterology·Guido CostamagnaAndrea Tringali
Apr 3, 2007·Gastrointestinal Endoscopy Clinics of North America·Jeremy S Rochester, David L Jaffe
Jan 20, 2007·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Takeshi TsujinoMasao Omata
Nov 21, 2015·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Chi Hyuk Oh, Seok Ho Dong
Nov 28, 2006·Best Practice & Research. Clinical Gastroenterology·Djamila Boerma, Matthijs P Schwartz
Jan 12, 2013·Journal of Hepato-biliary-pancreatic Sciences·Yasutoshi KimuraYuichi Yamashita
Jun 10, 2006·Gastroenterology·Renato CostiLeopoldo Sarli

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