Long-term follow-up of patients hospitalized for schizophrenia, 1913 to 1940

The Journal of Nervous and Mental Disease
J H StephensP R McHugh

Abstract

From a sample of 1357 schizophrenic patients hospitalized between 1913 and 1940 at the Phipps Clinic, we particularly studied 484 patients with follow-ups of 5 or more years. Of the sample of 1357 patients, 28 (10%) committed suicide. None of the suicides were included in the sample of 484, which also eliminated all patients with any previous psychiatric admissions or episodes of mental illness, even without hospitalization. On follow-up, only 13% of the 484 were rated recovered, whereas 58% were rated unimproved. Long-term global follow-up was highly correlated with discharge status. Subgroups retrospectively diagnosed by DSM-IV criteria were significantly related to long-term follow-up in the sample of 484 patients, there being a continuum of poor outcome ranging from the diagnoses schizophrenia through schizophreniform to schizoaffective. Poor follow-up was significantly correlated with poor premorbid history, gradual onset, lack of depressive symptoms and heredity, seclusive personality, lack of precipitating events, lack of confusion, single status, onset before age 21, delusions of control, onset 6 months or more before admission, and emotional blunting. These variables were used to construct a validated prognostic scale....Continue Reading

References

Jan 1, 1978·Schizophrenia Bulletin·J H Stephens
Jan 1, 1979·Schizophrenia Bulletin·W T Carpenter, J H Stephens
Jan 1, 1992·Schizophrenia Bulletin·R RamJ E Schwartz
Mar 1, 1991·Archives of General Psychiatry·B J CaroneJ F Westermeyer
Feb 1, 1991·The Journal of Nervous and Mental Disease·J H Stephens, P R McHugh
Mar 31, 1989·Science·R M DawesP E Meehl
Mar 1, 1989·Comprehensive Psychiatry·G Winokur, A Kadrmas
Jan 1, 1988·Schizophrenia Bulletin·J K Wing
Dec 1, 1986·The Journal of Nervous and Mental Disease·J H StephensL Covi
Dec 1, 1985·The American Journal of Psychiatry·R K Ries
May 2, 1974·The New England Journal of Medicine·S Siegal
Apr 1, 1966·The American Journal of Psychiatry·J H StephensJ C Mangrum
Nov 1, 1982·The Journal of Nervous and Mental Disease·J H StephensW T Carpenter
Oct 1, 1994·The American Journal of Psychiatry·J D HegartyG Oepen
May 1, 1996·The American Journal of Psychiatry·Y R ChenD B Burt
Nov 1, 1964·Archives of General Psychiatry·G E VAILLANT

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Citations

Feb 10, 1999·The Journal of Nervous and Mental Disease·J H StephensP R McHugh
May 2, 2000·The Journal of Nervous and Mental Disease·J H StephensP R McHugh
May 1, 2013·Clinical Psychology Review·Emily EisnerChristine Barrowclough
Sep 10, 2008·Brain Research·Sujatha NarayanElizabeth A Thomas
Apr 28, 2017·Early Intervention in Psychiatry·Johanna ImmonenJouko Miettunen
Jul 13, 2001·Journal of Psychopharmacology·S G Siris
Jan 12, 2008·International Journal of Methods in Psychiatric Research·Maria MattssonYvonne Forsell
Nov 4, 2000·The British Journal of Psychiatry : the Journal of Mental Science·M HarrowE W Davies
Feb 24, 2006·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·Martin Harrow, Thomas H Jobe
Feb 24, 2006·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·Thomas H Jobe, Martin Harrow
Feb 9, 2021·Psychological Medicine·Martin HarrowLiping Tong
Oct 24, 2020·BMC Medical Genetics·Evgeniya G PoltavskayaSvetlana A Ivanova
Jun 12, 2021·Journal of Psychiatric Research·Umit Haluk YesilkayaDerya Ipekcioglu

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