Long-term follow-up of patients with atopic keratoconjunctivitis

Ophthalmology
W J PowerC S Foster

Abstract

This study aimed to review the presenting features, treatment administered to, histopathologic findings, and complications encountered in a cohort of patients with atopic keratoconjunctivitis. The study design was a retrospective cohort series. The medical records of 20 patients with atopic keratoconjunctivitis and a minimum follow-up of 3 years were reviewed. Conjunctival and corneal complications, visual acuity before and after surgery, and histopathologic features on conjunctival biopsy were measured. Significant keratopathy developed in 70% of patients, corneal neovascularization in 60%, fornix foreshortening in 25%, and symblepharon in 20% during the course of their disease. Eleven patients (12 eyes) required penetrating keratoplasty (3 for tectonic purposes and 8 for visual rehabilitation). Vision improved by four or more lines of Snellen acuity in four eyes, improved by two lines in two eyes, remained the same in five eyes, and worsened by two lines in one eye after keratoplasty. Cataract surgery was performed in seven patients (nine eyes) with vision improving by four or more lines in six patients (eight eyes). Atopic keratoconjunctivitis is a potentially blinding disease that may result in a poor visual outcome as a re...Continue Reading

References

Aug 1, 1976·Archives of Dermatology·F J CarapetoR E Jordon
Nov 1, 1975·The Journal of Allergy and Clinical Immunology·S J McGeady, R H Buckley
Aug 1, 1977·American Family Physician·C C Huntley
Aug 1, 1991·Ophthalmology·C S FosterJ E Dutt
Feb 1, 1991·Ophthalmology·S J TuftR J Buckley
Jan 1, 1985·International Ophthalmology Clinics·L F Rich, J M Hanifin
Jan 1, 1984·International Ophthalmology Clinics·L S Braude, J W Chandler
Sep 1, 1981·The Journal of Clinical Investigation·R S GehaF S Rosen
Jan 1, 1981·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·M RaoP Steiner
Mar 1, 1994·The British Journal of Dermatology·C S MunroP S Friedmann
Jan 1, 1993·Documenta Ophthalmologica. Advances in Ophthalmology·C S FosterA Merchant
Jan 1, 1993·Annual Review of Immunology·Y MinamiT Taniguchi
Nov 1, 1995·Ophthalmology·I Tugal-TutkunC S Foster
Jan 1, 1994·Ocular Immunology and Inflammation·Y A AkovaC S Foster

❮ Previous
Next ❯

Citations

Apr 5, 2005·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·E M Messmer
Dec 21, 2002·Transplantation Proceedings·S L HargraveJ Niederkorn
Dec 24, 2005·Cornea·Antoine LabbeChristophe Baudouin
Sep 20, 2005·The British Journal of Ophthalmology·S Tatlipinar, E K Akpek
Mar 21, 2006·The British Journal of Ophthalmology·M DaniellH R Taylor
Aug 12, 2014·Current Opinion in Allergy and Clinical Immunology·Nancy J Reyes, Daniel R Saban
Jun 7, 2012·Eye & Contact Lens·Natalia PastoraAlmudena Hierro-Zarzuelo
Sep 18, 2007·Current Opinion in Allergy and Clinical Immunology·Margarita Calonge, José M Herreras
Jan 21, 2014·American Journal of Ophthalmology·Abdulrahman Mohammed Al-Amri
Jul 31, 2013·Journal français d'ophtalmologie·Y BenayounP-Y Robert
Nov 29, 2005·The Medical Clinics of North America·Leonard Bielory
Mar 22, 2016·Journal français d'ophtalmologie·O LevyN Bouheraoua
Dec 18, 2013·Journal of the American Academy of Dermatology·Joseph J ChenStephen C Pflugfelder
Aug 17, 2001·Current Opinion in Ophthalmology·H G Faraj, T Hoang-Xuan
Aug 17, 2001·Current Opinion in Ophthalmology·J H ChangD T Azar
Feb 20, 2008·Immunology and Allergy Clinics of North America·Leonard Bielory
Aug 22, 2008·Ocular Immunology and Inflammation·Harold Choi, Sao Bing Lee
Nov 19, 2017·Journal of Clinical Apheresis·Brendan C GrahamJeffrey L Winters
Sep 14, 2012·The Cochrane Database of Systematic Reviews·Julio J González-LópezGema Rebolleda Fernández
Sep 7, 2018·Ocular Immunology and Inflammation·Canan Asli UtineEsen Karamursel Akpek
Sep 18, 2018·Current Opinion in Ophthalmology·Nimesh PatelAnat Galor
Jun 27, 2018·Eye & Contact Lens·Hüseyin KayaBarbaros Şahin
Jun 23, 2020·Acta Ophthalmologica·Shih-Feng WengYuh-Shin Chang
Jul 1, 2020·Expert Opinion on Pharmacotherapy·Ibtesham T HossainBita Manzouri
Jul 1, 1999·Current Opinion in Ophthalmology·N Preschel, D R Hardten
Mar 12, 2017·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·P MaierT Reinhard
Feb 10, 2018·Case Reports in Ophthalmology·Passara Jongkhajornpong, Wannada Laisuan
Aug 26, 2010·Ocular Immunology and Inflammation·Canan Asli UtineEsen K Akpek
Oct 5, 2020·The British Journal of Ophthalmology·Ren-Long JanYuh-Shin Chang
Oct 22, 2020·The Cochrane Database of Systematic Reviews·Soyang Ella KimAnnegret Dahlmann-Noor
Jan 25, 2021·Experimental Eye Research·Ruchi ShahAlexander V Ljubimov
Jun 22, 2021·Frontiers in Medicine·Ren-Long JanYuh-Shin Chang

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atopic Dermatitis

Atopic dermatitis is a chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. Discover the latest research on atopic dermatitis here.

Cell Atlas of the Human Eye

Constructing a cell atlas of the human eye will require transcriptomic and histologic analysis over the lifespan. This understanding will aid in the study of development and disease. Find the latest research pertaining to the Cell Atlas of the Human Eye here.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Basophils

Basophils are myeloid cells with a high affinity IgE receptor and is involved in inflammatory responses during allergy. Discover the latest research on Basophils here.