PMID: 8959953Dec 1, 1996Paper

Long-term follow-up of patients with cutaneous T-cell lymphoma treated with extracorporeal photochemotherapy

Journal of the American Academy of Dermatology
J A ZicL E King

Abstract

Few studies have assessed the long-term outcome of patients with cutaneous T-cell lymphoma (CTCL) treated with extracorporeal photochemotherapy (ECP). Our objective was to assess the efficacy, safety, and survival of a cohort of patients with refractory T-cell lymphoma in various stages of cutaneous involvement who were treated with ECP. Twenty patients who had received at least 6 months of ECP between September 1988 and April 1991 were reevaluated and the data analyzed statistically to obtain outcome data through December 1995. A complete response (disappearance of all lesions) was obtained in five patients (25%) and a partial response (disappearance of at least 50% of lesions) in five patients (25%). Of the 10 responders, seven (70%) were weaned from ECP. Two of seven patients had a relapse. Ten patients (50%) showed no response to ECP. No statistically significant differences between responders and nonresponders were found with respect to demographic, clinical, or laboratory variables. Seven patients died of causes directly related to CTCL and two patients died of unrelated causes. Median survival time for the entire cohort was 96 months (range, 16 to 152 months). An assessment of early response after 6 to 8 months of ECP ha...Continue Reading

References

Sep 1, 1992·Journal of the American Academy of Dermatology·P HealdR Edelson
Nov 11, 1992·Journal of the American Academy of Dermatology·J ZicL E King
Nov 1, 1990·Journal of the American Academy of Dermatology·S ArmusE Bisaccia
Mar 1, 1989·Journal of the American Academy of Dermatology·E C VonderheidE J Van Scott
Jan 1, 1987·Journal of the American Academy of Dermatology·I M BravermanT Maynard
Jun 1, 1988·The Keio Journal of Medicine·P W Heald, R L Edelson
Jul 1, 1988·JAMA : the Journal of the American Medical Association·M A Weinstock, J W Horm
Feb 5, 1987·The New England Journal of Medicine·R EdelsonG Plewig
Mar 1, 1983·Clinical and Experimental Dermatology·M D CatterallP E Coode
Feb 1, 1984·Journal of the American Academy of Dermatology·H HönigsmannK Wolff
Sep 1, 1983·Journal of the American Academy of Dermatology·H S ZackheimW R Crain
Sep 1, 1983·International Journal of Radiation Oncology, Biology, Physics·A A TadrosA T Figueredo
Feb 1, 1982·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·M J BorowitzJ Burchette
Dec 1, 1982·American Journal of Clinical Oncology·M M OkenP P Carbone
Jun 1, 1981·Cancer·S B GreenS I Lamberg
Nov 1, 1994·Journal of the American Academy of Dermatology·J J HerrmannH H Roenigk
Jul 1, 1995·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·H W Lim, H R Harris
Aug 1, 1995·Journal of the American Academy of Dermatology·J J HerrmannS T Rosen
Sep 1, 1995·Archives of Dermatology·Y H KimR T Hoppe
Sep 1, 1995·Archives of Dermatology·H K KohR A Lew

❮ Previous
Next ❯

Citations

Dec 5, 1998·Seminars in Oncology Nursing·E Samuelson
Mar 31, 1999·Journal of Dermatological Science·K Danno
May 19, 1998·Trends in Biochemical Sciences·D A SinclairL Guarente
Jul 20, 2002·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Michael GirardiRichard Edelson
Jul 20, 2002·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Lars E French, Alain H Rook
Mar 7, 2003·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·R Knobler, C Jantschitsch
Jul 25, 2000·The British Journal of Dermatology·E A Coors, P von den Driesch
May 1, 2001·International Journal of Dermatology·G G Russo, C Mullen
Mar 18, 1999·Therapeutic Apheresis : Official Journal of the International Society for Apheresis and the Japanese Society for Apheresis·J A ZicL E King
Dec 22, 2011·Current Opinion in Oncology·John A Zic
Nov 30, 1999·Photodermatology, Photoimmunology & Photomedicine·S B JiangH W Lim
Jun 30, 2004·Leukemia & Lymphoma·D A PichardoS T Rosen
Nov 27, 2015·American Journal of Hematology·Ryan A Wilcox
May 12, 2012·Actas dermo-sifiliográficas·R M Izu-Belloso, J C García-Ruiz
Nov 10, 2011·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Maria AttaPanagiotis Tsirigotis
Jul 29, 2008·Journal of the American Academy of Dermatology·Suzanne ArulogunChristopher McCormack
Sep 11, 2007·The Nursing Clinics of North America·Sue A McCann
Sep 7, 2007·Photodermatology, Photoimmunology & Photomedicine·Janine D MillerElma D Baron
Oct 13, 2011·American Journal of Hematology·Ryan A Wilcox
Sep 14, 2012·Photodermatology, Photoimmunology & Photomedicine·Robert KnoblerLarisa Geskin
Jul 16, 2010·Photodermatology, Photoimmunology & Photomedicine·Laura Y McGirtEric C Vonderheid
Dec 21, 2013·Journal of the European Academy of Dermatology and Venereology : JEADV·R KnoblerU Hillen
Jul 22, 2014·American Journal of Hematology·Ryan A Wilcox
Apr 26, 2006·Journal of the American Academy of Dermatology·Robert M KnoblerUNKNOWN Systemic Sclerosis Study Group
Mar 7, 2006·Seminars in Oncology·Francine Foss
Apr 1, 2006·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Franz TrautingerSean Whittaker
Apr 3, 1999·Journal of the American Academy of Dermatology·B PrinzG Plewig
Mar 5, 1998·Journal of the American Academy of Dermatology·E C VonderheidM A Wasik
Jan 9, 2004·Hematology/oncology Clinics of North America·Marie-France DemierreHerschel S Zackheim
May 20, 2005·Clinical Oncology : a Journal of the Royal College of Radiologists·V McFarlaneT M Illidge
Oct 16, 2016·International Journal of Clinical Oncology·Helen Ma, Maher Abdul-Hay
Mar 5, 2003·Technology in Cancer Research & Treatment·Michael GirardiRichard L Edelson
Sep 13, 2012·The Annals of Pharmacotherapy·Miryoung KimCindy L O'Bryant
Nov 18, 2003·The Australasian Journal of Dermatology·H Miles PrinceChris Baker
Dec 23, 2003·Dermatologic Therapy·John A Zic

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