Long-term follow-up of patients with hyperprolactinaemia

Clinical Endocrinology
W J JeffcoateJ Lambourne

Abstract

To determine the frequency with which hyperprolactinaemic illness tends to resolve with time. A retrospective case-notes review from a specialist endocrine unit in a provincial teaching hospital and tertiary referral centre. Seventy women with hyperprolactinaemia referred to the unit in the 15 year period between May 1979 and May 1994. All those with a non-pituitary cause or with macroadenoma had been excluded, as were those who did not have high-resolution imaging, or who were on treatment at the time of referral. Intermittent course of treatment with dopamine receptor agonists according to individual need. Latest serum PRL concentration in those who had discontinued treatment, and whether serum PRL tended to be lower in any particular group. There was a significant fall in median PRL concentration from 2000 (714-8000) to 1000 mU/l (220-5600) in the 31 women who had discontinued therapy (P < 0.0005), and serum PRL was normal (< 700 mU/l) in 11 of them. Serum PRL also fell to normal in three of ten women who had no treatment at all. Final PRL concentration was normal in 35% of women who had had at least one pregnancy during the period of follow-up compared to 14% who had not (P < 0.05). These data confirm the findings of others...Continue Reading

Citations

Feb 16, 2005·Reviews in Endocrine & Metabolic Disorders·David M Cook
May 19, 2001·Surgical Neurology·H NishiokaA Hirano
May 24, 2003·Frontiers in Neuroendocrinology·Andy Levy, Stafford Lightman
Apr 20, 1999·Endocrinology and Metabolism Clinics of North America·M E Molitch
Sep 27, 2001·Endocrinology and Metabolism Clinics of North America·M E Molitch
Apr 12, 2001·Clinical Endocrinology·S KarunakaranJ A Wass
Nov 25, 2003·The New England Journal of Medicine·Janet A Schlechte
Apr 2, 2010·The New England Journal of Medicine·Anne Klibanski
Nov 25, 2003·The New England Journal of Medicine·Annamaria ColaoGaetano Lombardi
Sep 17, 2003·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Omar SerriShereen Ezzat
Jul 3, 2004·Current Opinion in Obstetrics & Gynecology·Julian R E Davis
Sep 26, 2000·BJOG : an International Journal of Obstetrics and Gynaecology·H S RandevaG M Prelevic
Jul 26, 2012·Systematic Reviews·Amy T WangMohammad Hassan Murad
Apr 2, 2009·The Journal of Clinical Endocrinology and Metabolism·J KharlipG S Wand
Jun 12, 2004·Neurosurgical Focus·James K Liu, William T Couldwell
Nov 1, 2005·Neurosurgical Focus·John A Jane
Feb 11, 1999·Journal of Endocrinological Investigation·P TouraineF Kuttenn
Nov 24, 2011·Endocrinology and Metabolism Clinics of North America·Amal Shibli-Rahhal, Janet Schlechte
Dec 1, 2009·Best Practice & Research. Clinical Endocrinology & Metabolism·Annamaria Colao
May 16, 2009·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Chirag G PatilSteven D Chang
Jan 30, 2008·Endocrinology and Metabolism Clinics of North America·Andy Levy
Sep 25, 2007·Best Practice & Research. Clinical Obstetrics & Gynaecology·V K B Prabhakar, J R E Davis
Mar 24, 2009·Journal of Neuroendocrinology·L A Nolan, A Levy
Aug 5, 2006·Clinical Endocrinology·Felipe F CasanuevaAndrea Giustina
Nov 22, 2013·Clinical Endocrinology·Marie-Eve DomingueDominique Maiter
Apr 17, 2012·Annales d'endocrinologie·Dominique Maiter, Vanessa Primeau
Apr 15, 2003·Neurosurgery Clinics of North America·Marie F Simard
May 29, 2007·Annales d'endocrinologie·P ChansonB Estour
Jul 26, 2000·Baillière's Best Practice & Research. Clinical Endocrinology & Metabolism·A Levy
Jul 26, 2000·Baillière's Best Practice & Research. Clinical Endocrinology & Metabolism·J Webster
Sep 18, 2009·Orvosi hetilap·Emese Mezosi, Orsolya Nemes
May 1, 2016·Annales d'endocrinologie·Dominique Maiter
Jan 30, 2008·Endocrinology and Metabolism Clinics of North America·Tatiana ManciniAndrea Giustina
Apr 13, 2000·Clinical Endocrinology·A Levy
Dec 3, 2016·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Ashu RastogiAnil Bhansali
Nov 28, 2017·Endocrine·Deirdre Cocks EschlerEliza B Geer
Mar 23, 2011·Nature Reviews. Endocrinology·Annamaria Colao, Silvia Savastano
Aug 19, 2018·Clinical Chemistry and Laboratory Medicine : CCLM·Verena GoundenIshwarlal Jialal
Dec 9, 2003·The Journal of Clinical Investigation·Shlomo Melmed
Aug 26, 1998·The Journal of Clinical Endocrinology and Metabolism·A ColaoG Lombardi
Aug 8, 2007·The Journal of Clinical Endocrinology and Metabolism·Janet A Schlechte
Jul 9, 2009·The Journal of Clinical Endocrinology and Metabolism·Anne Klibanski
Jul 1, 2009·Expert Review of Endocrinology & Metabolism·Amir HamrahianLaurence Kennedy

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