Long-term follow-up of renal arteries after radio-frequency catheter-based denervation using optical coherence tomography and angiography

The International Journal of Cardiovascular Imaging
Tomasz RolederWojciech Wojakowski

Abstract

Optical coherence tomography (OCT) imaging at the time of renal denervation (RDN) showed that procedure might cause spasm, intimal injury or thrombus formation. In the present study, we assessed the healing of renal arteries after RDN using OCT and renal angiography in long-term follow-up. OCT and renal angiography were performed in 12 patients (22 arteries) 18.41 ± 5.83 months after RNS. There were no adverse events or complications during the long-term follow-up. In ten patients (83 %), significant reductions of blood pressure was achieved without a change of the antihypertensive medications. We demonstrated the presence of 26 areas of focal intimal thickening identified by OCT in 10 (83 %) patients and in 14 (63 %) arteries. The mean area of focal intimal thickening was 0.054 ± 0.033 mm(2). No vessel dissection, thrombus, intimal tear or acute vasospasm were observed during the OCT analysis. Also, the quantitative angiography analysis revealed a significant reduction of the minimal and proximal lumen diameters at follow-up as compared to measurements obtained before RDN. Renal arteries have a favorable "long-term" vessel healing response after RDN. Focal intimal thickening and a modest reduction of the minimal lumen diameter...Continue Reading

References

Jan 1, 1988·Acta Physiologica Scandinavica·E D HögestättC M Kullendorff
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Jul 29, 2011·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Marian K RippyChristopher K Zarins
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Mar 26, 2014·Hypertension·Fernando Jaén ÁguilaCelia Fernández-Torres
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May 28, 2015·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Janusz KochmanGrzegorz L Kaluza

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Citations

Mar 1, 2019·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Chuanyu GaoJiguang Wang
Jun 20, 2020·European Journal of Medical Research·Linwei ZhaoChuanyu Gao

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