PMID: 20623466Jul 14, 2010Paper

Long-term follow-up of spontaneous retinal pigment epithelium tears in age-related macular degeneration treated with anti-VEGF therapy

European Journal of Ophthalmology
Sebastian P LesniakDaniel B Roth

Abstract

To describe the clinical response following anti-vascular endothelial growth factor (VEGF) therapy in patients with spontaneous retinal pigment epithelium (RPE) tears secondary to age-related macular degeneration (AMD). Retrospective chart review of patients with AMD who developed a spontaneous RPE tear and were subsequently treated with anti-VEGF therapy at a single institution. In 5 patients included in the study, the median number (range) of injections received was 14.2 (5-18). The median baseline acuity was 20/200, which remained stable at 12 months and improved to 20/60 at 24 months. These changes were not statistically different. Anti-VEGF therapy appears safe in eyes with spontaneous RPE tear secondary to AMD and may help to stabilize or even improve acuity in some cases.

References

Jun 1, 1981·The British Journal of Ophthalmology·A HoskinK Sehmi
Dec 8, 2006·Retina·Enrico PeirettiLawrence A Yannuzzi
Feb 24, 2007·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Maria Andreea GamulescuHelmut Sachs
May 29, 2007·Progress in Retinal and Eye Research·Susanne BinderCarl Glittenberg
Jun 15, 2007·Retina·Louis K Chang, David Sarraf
Jan 29, 2009·Retina·Bradley T SmithRajendra S Apte

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Citations

Mar 1, 2015·Current Ophthalmology Reports·Aleksandra V Rachitskaya, Raquel Goldhardt
Jun 20, 2012·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·Rosa M CocoMarta Fernández Muñoz
Mar 3, 2021·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Rodrigo Vilares-MorgadoÂngela Carneiro

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