PMID: 15359385Sep 11, 2004Paper

Long-term follow-up status of patients with neuroblastoma after undergoing either aggressive surgery or chemotherapy--a single institutional study

Journal of Pediatric Surgery
Masayuki KubotaTeruhiro Watanabe

Abstract

Before adopting a national protocol of aggressive chemotherapy for patients with advanced neuroblastoma in 1985, the treatment strategies in use varied considerably among the institutions in Japan. An aggressive surgical resection was the treatment of choice at the authors' institution before 1985. To better understand treatment-related complications, the authors retrospectively investigated the long-term morbidity of patients who had reached adulthood. Sixteen patients with neuroblastoma currently 18 years of age or older were incorporated into the study. All were non-mass screening cases, and 13 of the patients had undergone aggressive surgery, whereas the remaining 3 cases had received aggressive chemotherapy. In the 13 patients who had undergone aggressive surgical treatment, a unilateral atrophy of the kidney was noted in 2 cases of adrenal and retroperitoneal neuroblastomas, respectively. Dry ejaculation was noted in one case of a giant presacral neuroblastoma. A maldevelopment of the unilateral lower extremity was also noted in another case with a presacral tumor, which had been resected by abdominal and sacral approaches. In the 3 patients who had undergone aggressive chemotherapy, severe hearing loss occurred in 2 case...Continue Reading

References

Aug 1, 1991·Radiology·D L DayB A Alford
Sep 1, 1996·Journal of Pediatric Surgery·M TanabeH Takahashi
May 30, 2001·International Journal of Pediatric Otorhinolaryngology·P StavroulakiG Adamopoulos
Jul 4, 2002·Molecular Therapy : the Journal of the American Society of Gene Therapy·William J BowersRobert D Frisina
Oct 9, 2002·European Journal of Pediatric Surgery : Official Journal of Austrian Association of Pediatric Surgery ... [et Al] = Zeitschrift Für Kinderchirurgie·Z ZachariouA Zavitzanakis
Nov 20, 2002·Journal of Pediatric Hematology/oncology·Michio KanekoSachiyo Suita
Dec 4, 2002·Medical and Pediatric Oncology·Toshiji ShitaraMinoru Kuroiwa
Jan 28, 2003·European Journal of Pediatric Surgery : Official Journal of Austrian Association of Pediatric Surgery ... [et Al] = Zeitschrift Für Kinderchirurgie·D von SchweinitzF Berthold
Mar 8, 2003·International Journal of Pediatric Otorhinolaryngology·Masa-aki Teranishi, Tsutomu Nakashima

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Citations

May 25, 2010·Surgery Today·Masayuki Kubota
Jun 1, 2012·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Lisa B KenneyLillian Meacham
Mar 24, 2010·Surgical Oncology·Steven W WarmannJoerg Fuchs
Feb 19, 2008·Journal of Pediatric Surgery·Thambipillai Sri ParanMichael P La Quaglia
Apr 28, 2011·Pediatric Blood & Cancer·Adeline SalimPaul D Losty
Apr 2, 2016·Nature Reviews. Endocrinology·Susan R RoseSarah D Corathers
May 30, 2015·Bulletin du cancer·Christian PiolatSabine Sarnacki
May 26, 2015·Cell and Tissue Research·Peter M Vila, Judith E C Lieu
May 28, 2019·Expert Review of Endocrinology & Metabolism·Jonathan C Howell, Susan R Rose
Jan 30, 2018·Japanese Journal of Clinical Oncology·Akira NakagawaraMasanori Nishi

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