Long-term intake of dietary fiber and decreased risk of cholecystectomy in women

The American Journal of Gastroenterology
Chung-Jyi TsaiEdward L Giovannucci

Abstract

Epidemiologic studies on the relationship between dietary fiber and gallstone disease are inconclusive, and the effects of different types of dietary fiber are not clear. We examined the association between long-term intake of dietary fiber as well as fiber from different sources and risk of cholecystectomy in a cohort of 69,778 women who were aged from 35 to 61 years in 1984 and had no history of gallstone disease. As part of the Nurses' Health Study, the women reported on questionnaires mailed to them every two years both their fiber intake and whether they had undergone cholecystectomy. During 16 yr of follow-up, we documented 5,771 cases of cholecystectomy. After adjusting for age and other known or suspected risk factors in a multivariate model, compared with women in the lowest quintile of total dietary fiber intake, the relative risk of choleystectomy for those in the highest quintile was 0.87 (95% CI, 0.78-0.96, p for trend = 0.005). For a 5-g increase in total fiber intake, the multivariate relative risk was 0.94 (95% CI, 0.90-0.98). Insoluble fiber, taking soluble fiber into account in the multivariate model, was significantly associated with a reduced risk. The multivariate relative risk was 0.83 (95% CI, 0.73-0.94, ...Continue Reading

References

Jun 1, 1990·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·J X ZhangE Westerlund
Jan 1, 1987·Scandinavian Journal of Gastroenterology. Supplement·J G WechslerH Ditschuneit
Jul 1, 1982·The American Journal of Clinical Nutrition·I H Ullrich, M J Albrink
Aug 15, 1994·American Journal of Epidemiology·E J FeskensD Kromhout
Mar 1, 1994·The American Journal of Clinical Nutrition·U Smith
May 1, 1994·The American Journal of Clinical Nutrition·D B HunninghakeR R O'Connor
Jan 1, 1997·Scandinavian Journal of Gastroenterology. Supplement·G P VanBerge-HenegouwenK J van Erpecum
May 18, 1999·American Journal of Surgery·W H SchwesingerR Johnson
Feb 3, 2000·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·C E Ruhl, J E Everhart
Jan 13, 2001·BMJ : British Medical Journal·I J Beckingham
Sep 26, 2002·Epidemiology·K J Rothman
Mar 8, 2003·Alimentary Pharmacology & Therapeutics·J-Y KangJ D Maxwell

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Citations

Oct 16, 2009·Pediatric Surgery International·Andrea BischoffAlberto Peña
Aug 25, 2009·BMC Gastroenterology·John HuangPo-Huang Lee
Aug 22, 2016·European Journal of Nutrition·Caroline NordenvallAlicja Wolk
Jul 26, 2017·The American Journal of Gastroenterology·Amélie BarréMarie-Christine Boutron-Ruault
Jul 8, 2011·Digestive Diseases·Caroline S StokesFrank Lammert
Sep 19, 2018·Nutrients·Isabel Gutiérrez-DíazSonia González
Feb 22, 2008·The American Journal of Gastroenterology·Cynthia W Ko
Mar 7, 2008·Current Treatment Options in Gastroenterology·Chad I Williams, Eldon A Shaffer
Apr 2, 2009·Nutrition Reviews·James W AndersonChristine L Williams
Nov 28, 2014·Journal of Translational Medicine·Saima GulMuhammad Zia-Ul-Haq
Feb 23, 2019·Expert Review of Gastroenterology & Hepatology·Agostino Di CiaulaPiero Portincasa
Nov 13, 2020·Nutrición hospitalaria·Ayşegül Bükülmez, Lütfi Molon
Nov 28, 2006·Best Practice & Research. Clinical Gastroenterology·Niels G Venneman, Karel J van Erpecum
Mar 1, 2008·Journal of Hepatology·Frank Lammert, Juan-Francisco Miquel
May 19, 2010·Gastroenterology Clinics of North America·Agostino Di CiaulaPiero Portincasa
Sep 21, 2021·Visceral Medicine·Caroline Sarah Stokes, Frank Lammert

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