Long-term intrathecal Baclofen infusion in supraspinal spasticity of adulthood

Acta Neurologica Scandinavica
A DarioG Bono

Abstract

To evaluate long-term results of chronic intrathecal Baclofen infusion on the spasticity, on the spasms and to evaluate the side-effects of the intrathecal Baclofen in patients with supraspinal spasticity. Fourteen patients with severe progressive refractory to medical therapy spasticity were evaluated after chronic intrathecal Baclofen infusion performed by implantation of subcutaneous pump. The patients had suffered traumatic or anoxic acquired brain injuries. The clinical evaluation was made using Ashworth Scale (AS) and the Spasm Frequency Scale (SFS). The intrathecal therapy showed a statistically significant improvement of the tone and of the spasms. The intrathecal infusion of Baclofen seems to be an effective treatment in patients with supraspinal spasticity.

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Citations

Jul 1, 2008·Neuromodulation : Journal of the International Neuromodulation Society·Elmar M DelhaasNiek S Klazinga
Mar 17, 2007·Brain Injury : [BI]·Shawn MarshallMark Bayley
Sep 18, 2009·Developmental Medicine and Child Neurology·Linda E Krach
Jul 1, 2010·Acta Neurologica Scandinavica. Supplementum·T Rekand
Feb 17, 2015·Chirality·Vinod Kumar Vashistha, Ravi Bhushan
Jul 20, 2016·Neuromodulation : Journal of the International Neuromodulation Society·Michael SaulinoAaron L Boster
Sep 7, 2006·Neurosurgery·Todd D McCall, Joel D MacDonald
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Sep 29, 2018·Brain and Behavior·Elke Pucks-FaesLeopold Saltuari
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May 16, 2018·Brain and Behavior·Elke Pucks-FaesLeopold Saltuari
May 10, 2017·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Antonio De TantiUNKNOWN ITB Italian Group
Jan 16, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Qingfeng HeDaryl J Murry
Sep 23, 2020·Biomedical Chromatography : BMC·Sonika SethiRavi Bhushan
Feb 6, 2021·Archives of Rehabilitation Research and Clinical Translation·Elke Pucks-FaesLeopold Saltuari

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