Long-Term Mortality and Early Valve Dysfunction According to Anticoagulation Use: The FRANCE TAVI Registry

Journal of the American College of Cardiology
Pavel OvertchoukJean-Philippe Collet

Abstract

The optimal antithrombotic treatment after transcatheter aortic valve replacement (TAVR) remains a matter of debate. Although dual antiplatelet therapy is recommended, single antiplatelet therapy or oral anticoagulation is frequently used according to the patient profile. Whether this approach may affect clinical outcome is unknown. FRANCE TAVI (French Transcatheter Aortic Valve Implantation) is a prospective, multicenter, nationwide French registry. The study objectives were to identify independent correlates of long-term all-cause mortality and early bioprosthetic valve dysfunction (BVD), defined as increased prosthetic gradient ≥10 mm Hg or new gradient ≥20 mm Hg. To account for missing values, multiple imputations were performed. Stepwise multivariable Cox regression and logistic regression were used for all-cause mortality and bioprosthesis valve dysfunction was used, respectively. Sensitivity analysis retaining only patients with complete data were also performed. Of 12,804 patients included in the registry between January 1, 2013, and December 31, 2015, a total of 11,469 (mean ± SE age: 82.8 ± 0.07 years; logistic European System for Cardiac Operative Risk Evaluation: 17.8 ± 0.1%; mean duration of follow-up: 495 ± 3.5 da...Continue Reading

Citations

Nov 28, 2018·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Paul Guedeney, Roxana Mehran
Jan 3, 2019·European Heart Journal·Wojciech Wojakowski, Helmut Baumgartner
Sep 28, 2018·Minerva cardioangiologica·Pawel Kleczynski
Mar 6, 2019·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Hidenori KomiyamaPatrick W Serruys
May 24, 2019·Circulation Journal : Official Journal of the Japanese Circulation Society·Koichi MaedaYoshiki Sawa
Nov 17, 2019·The New England Journal of Medicine·George D DangasUNKNOWN GALILEO Investigators
Sep 10, 2019·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Tobias RheudeMichael Joner
Apr 1, 2020·Diagnostics·Francesco NappiFerdinando Auricchio
Mar 15, 2019·Heart·Vincent Johan NijenhuisJurrien Maria Ten Berg
May 23, 2020·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Shawn X LiSammy Elmariah
Sep 19, 2019·Cardiovascular Intervention and Therapeutics·Hiroshi OnodaKoichiro Kinugawa
Jul 8, 2020·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Timothy F SimpsonScott M Chadderdon
Sep 5, 2020·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Giuseppe TarantiniOlaf Wendler
Sep 16, 2020·European Heart Journal·Arnold C T NgJeroen J Bax
May 9, 2019·Advances in Therapy·Katie LindenIan B A Menown
Apr 22, 2020·Herz·Robert Michael NechwatalAxel Schlitt
Jun 15, 2019·Expert Review of Cardiovascular Therapy·Antonio GrecoDavide Capodanno
Apr 14, 2020·Current Pharmaceutical Design·M DrakopoulouΚ Toutouzas
Oct 12, 2020·Current Cardiology Reports·Tarun ChakravartyRaj Makkar
Jan 5, 2021·Current Opinion in Cardiology·Janine EcksteinAsim N Cheema
Mar 3, 2020·Archives of Cardiovascular Diseases·Charles FauvelHélène Eltchaninoff
Oct 28, 2019·Annales de cardiologie et d'angéiologie·P Guedeney, J-P Collet
Apr 21, 2021·Circulation. Cardiovascular Interventions·Mirvat Alasnag, Gerald V Naccarelli
Aug 7, 2021·JACC. Cardiovascular Interventions·Davide CapodannoDominick J Angiolillo
Dec 19, 2020·Journal of Cardiothoracic and Vascular Anesthesia·Akira ShimokawaYoshihiko Ohnishi
Aug 1, 2021·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Nicolas M Van MieghemEberhard Grube
Nov 21, 2020·JACC. Cardiovascular Interventions·Jurrien M Ten Berg, Jorn Brouwer

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atrial Filbrillation

Atrial fibrillation refers to the abnormal heart rhythm characterized by rapid and irregular beating of the atria. Here is the latest research.

Cardiology Journals

Discover the latest cardiology research in this collection of the top cardiology journals.

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.