Long-term mortality and recurrent stroke risk among Chinese stroke patients with predominant intracranial atherosclerosis

Stroke; a Journal of Cerebral Circulation
Ka Sing Wong, Huan Li

Abstract

The goal of this study was to document the long-term outcome of ischemic stroke patients in a population with predominant intracranial atherosclerosis and risk factors for a recurrent event. Intracranial and extracranial arteries of consecutive patients with acute ischemic stroke were studied prospectively with transcranial Doppler and duplex ultrasound. All patients were followed up regularly for the development of recurrent stroke, cardiac event, or death. We included 705 patients with acute ischemic stroke, of whom 345 were documented ultrasonographically as having large-artery lesions. The follow-up period was up to 42 months (mean, 28+/-5 months). One hundred seventeen patients (17%) died of any cause, and 199 (28%) suffered further cerebrovascular cardiac events. The 3.5-year cumulative mortality rate was 20.8%; for cerebrovascular event, it was 29.5%. The annual recurrent stroke rates during the first year were 10.9% for patients without vascular lesion, 17.1% for intracranial atherosclerosis only, and 24.3% for both intracranial and extracranial atherosclerosis; for the second year, the rates were 7.5%, 8.6%, and 7.7%, respectively. More occurrence of death (log rank, 5.19; P=0.02) or cerebrovascular event (log rank, 9....Continue Reading

References

Apr 1, 1998·Neurology·K S Lawrence WongR Kay
Apr 3, 1999·JAMA : the Journal of the American Medical Association·P B GorelickD C Rhew
May 9, 2000·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·V L BabikianAndrei V Alexandrov
May 23, 2001·JAMA : the Journal of the American Medical Association·Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults

Citations

Mar 10, 2009·Journal of Neurology·Teng-Yeow TanTing-Yao Chen
Oct 31, 2013·Lancet·Colin P DerdeynStenting and Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis Trial Investigators
Apr 1, 2005·The New England Journal of Medicine·Walter J Koroshetz
Sep 9, 2011·The New England Journal of Medicine·Marc I ChimowitzSAMMPRIS Trial Investigators
Feb 19, 2009·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·Deidre Anne De SilvaC Chen
May 20, 2006·Cerebrovascular Diseases·J Martí-FàbregasE Palomeras
Jun 22, 2006·Cerebrovascular Diseases·Deidre Anne De SilvaChristopher Chen
Oct 29, 2010·Cerebrovascular Diseases·Joanna M WardlawVera Cvoro
Dec 27, 2007·Circulation Journal : Official Journal of the Japanese Circulation Society·Hon-Kan YipChing-Jen Wang
Oct 14, 2009·Circulation Journal : Official Journal of the Japanese Circulation Society·Ding DingChina Ischemic Stroke Registry Study (CISRS) investigators
Dec 20, 2012·Advances in Pharmacological Sciences·Sudeep KarveRajesh Balkrishnan
Sep 7, 2013·Lancet·A I Qureshi, Louis R Caplan
Sep 1, 2012·AJNR. American Journal of Neuroradiology·J S JeonB J Kwon
Nov 6, 2013·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Chunyan LeiYanchao Chen
Oct 15, 2013·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Mahesh KateBejoy Thomas
May 21, 2013·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Fang YangX Liu
Jul 10, 2010·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·B L ManK S Lawrence Wong
Dec 26, 2009·La Presse médicale·France Woimant
Nov 11, 2009·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Deidre Anne De SilvaMeng Cheong Wong
Nov 26, 2008·Neurologic Clinics·Qasim BashirVictor Aletich
Jul 22, 2008·American Journal of Ophthalmology·Ning CheungTien Y Wong
May 26, 2007·Journal of the Neurological Sciences·Deidre Anne De SilvaMeng Cheong Wong
Apr 23, 2009·International Journal of Stroke : Official Journal of the International Stroke Society·Vincent MokLawrence K S Wong
Aug 19, 2008·International Journal of Stroke : Official Journal of the International Stroke Society·Lawrence K S Wong
Jul 13, 2011·International Journal of Stroke : Official Journal of the International Stroke Society·Thomas W H LeungK S Lawrence Wong
Aug 11, 2012·Journal of Traditional Chinese Medicine = Chung I Tsa Chih Ying Wen Pan·Xiao-feng ZhaoShu Wang
May 10, 2015·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Ran MengXunming Ji
Jan 15, 2014·Journal of the Neurological Sciences·Yinyao LinZhengqi Lu
Jul 30, 2014·Frontiers in Neurology·Yuehua PuLiping Liu
May 2, 2014·Frontiers in Neurology·Ryan A McTaggart, Michael P Marks
Mar 1, 2006·Journal of Clinical Neurology·Kwang-Yeol ParkKyungmi Oh
Jun 22, 2016·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Ting ZhaoQing-Wu Yang
Jul 2, 2016·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Claudio BaracchiniGiorgio Meneghetti
Apr 30, 2014·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Janusz MaciaszekJacek Wojcikiewicz
Jan 10, 2017·International Journal of Stroke : Official Journal of the International Stroke Society·Yuehua PuLiping Liu
Sep 21, 2006·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Jing Hao HanKa Sing Wong
Aug 19, 2008·International Journal of Stroke : Official Journal of the International Stroke Society·Thomas W H LeungKa Sing Wong
May 3, 2015·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·Peng GaoF Ling
Apr 6, 2007·The Journal of International Medical Research·W ZhuH Zhang
Jul 2, 2017·World Neurosurgery·Lauren E Rotman, Mark R Harrigan
Nov 10, 2017·Interventional Neurology·Xiongjun HeYajie Liu
Jan 20, 2012·The Cochrane Database of Systematic Reviews·Sen LinWendan Tao
Aug 10, 2016·Journal of Neurointerventional Surgery·Sami Al KasabRaymond D Turner
Jul 27, 2017·Practical Neurology·James CaldwellP Alan Barber
Oct 15, 2014·Circulation·Katja RitzMat J A P Daemen
Apr 17, 2013·Journal of the American Heart Association·Aakriti GuptaHarlan M Krumholz
Aug 12, 2017·Stroke; a Journal of Cerebral Circulation·Byung-Su KimGyeong-Moon Kim
Aug 8, 2015·Stroke; a Journal of Cerebral Circulation·Seemant ChaturvediSAMMPRIS Trial Investigators
Feb 23, 2008·Stroke; a Journal of Cerebral Circulation·Mai N Nguyen-HuynhS Claiborne Johnston
Aug 1, 2009·Stroke; a Journal of Cerebral Circulation·Bik Ling ManKa Sing Wong
Aug 20, 2011·Stroke; a Journal of Cerebral Circulation·Qian JiaYongjun Wang
Apr 5, 2012·Circulation. Cardiovascular Quality and Outcomes·Keun-Hwa JungKorean Stroke Registry Study Group
Aug 31, 2012·Stroke; a Journal of Cerebral Circulation·Hyo Suk NamJi Hoe Heo
Sep 13, 2006·Archives of Neurology·Christian WeimarHans-Christoph Diener
Dec 6, 2005·Cerebrovascular Diseases·Juan F Arenillas, José Alvarez-Sabín
Dec 6, 2005·Cerebrovascular Diseases·José A Egido
Jan 24, 2020·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·Hugo CuellarRimal Hanif
Dec 25, 2019·The Journal of Clinical Hypertension·Xiaowei SongJian Wu
Mar 5, 2020·The International Journal of Neuroscience·Yi BaoSiqin Zhou
Jul 29, 2011·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Martin RoubecDavid Skoloudík
Jul 15, 2016·The International Journal of Neuroscience·Xiaowei SongYi Ren
Jan 19, 2019·Annals of Clinical and Translational Neurology·Wenbo ZhaoXunming Ji
Apr 3, 2019·Journal of Magnetic Resonance Imaging : JMRI·Daniel F ArteagaManus J Donahue
Jun 1, 2016·European Stroke Journal·James E SieglerESUS Global Registry Investigators
Jun 2, 2007·Stroke; a Journal of Cerebral Circulation·Janice E WilliamsWASID Investigators
Dec 31, 2019·Journal of Cerebrovascular and Endovascular Neurosurgery·Bo Seok KimSung Hyun Kim
Feb 5, 2014·The Tohoku Journal of Experimental Medicine·Hua-Fen ChenYiu-Tong Chu
Dec 2, 2016·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Yilan XuXihai Zhao
Jun 20, 2014·World Journal of Clinical Cases·Bik Ling Man, Yat Pang Fu
Oct 9, 2018·Stroke and Vascular Neurology·Wengui Yu, Wei-Jian Jiang
Nov 16, 2019·Current Treatment Options in Cardiovascular Medicine·Kyle C Kern, David S Liebeskind
Dec 4, 2020·International Journal of Stroke : Official Journal of the International Stroke Society·Robert Hurford, Peter M Rothwell

Related Concepts

Cause of Death
Intracranial Atherosclerosis
Relapse
Incidence Studies
Comorbidity
Cox Proportional Hazards Models
Survival Analysis
Ultrasonography, Doppler, Transcranial
Benefit-Risk Assessment
Acute Cerebrovascular Accidents

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