Long-term nutritional consequences of bowel segment use for lower urinary tract reconstruction in pediatric patients

Urology
N B KallooJ P Gearhart

Abstract

To identify whether nutritional abnormalities, specifically vitamin B12 deficiency, folate deficiency, and low carotene levels, are long-term sequelae of the use of ileum and/or colon for lower urinary tract reconstruction in pediatric patients. Serum levels of vitamin B12, methyl malonic acid (MMA), carotene, and folate were measured 3 to 13 years (mean 6) after surgery in patients less than 18 years old at the time of operation. Thirteen (44.8%) of 29 patients had abnormal nutritional serum levels, with 5 (38.5%) of 13 having more than one abnormal value. Vitamin B12 was low in 4 (14%) of 29 patients; MMA was abnormally high in 7 (26%) of 27; and both folate and carotene levels were low in 4 (14.8%) of 27. No patient with reconstruction with colon alone (n = 3) had abnormal values, and no patient had any clinical signs or symptoms of vitamin B12 deficiency or fat malabsorption. Nutritional abnormalities can occur in patients after lower urinary tract reconstruction with ileum. No patient in this study had symptomatic abnormalities; however, long-term clinical effects may be significant. The implications of low folate levels in women of childbearing age must also be taken into consideration because of the potential association...Continue Reading

References

Feb 1, 1992·The Nurse Practitioner·N W Esposito
Dec 1, 1991·Southern Medical Journal·E J Fine, E D Soria
Aug 1, 1989·The Journal of Urology·D A CanningJ P Gearhart
Jun 30, 1988·The New England Journal of Medicine·J LindenbaumR H Allen
Feb 1, 1993·The Journal of Urology·M S SteinerF F Marshall
Feb 1, 1968·The Journal of Clinical Investigation·W E Meihoff, F Kern
Feb 1, 1958·The Journal of Urology·L M ORRJ L CAMPBELL

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Citations

Mar 19, 2004·Current Urology Reports·Arthur Mourtzinos, Joseph G Borer
Mar 28, 2001·Journal of the American Dietetic Association·S M GrossH T Ireys
Oct 1, 2007·Indian Journal of Urology : IJU : Journal of the Urological Society of India·C R J Woodhouse
Mar 22, 2000·Current Opinion in Urology·C R Woodhouse
Mar 22, 2000·Current Opinion in Urology·A Stenzl
Nov 17, 2009·Primary Care·Kevin C OeffingerWendy Landier
May 11, 1999·Journal of Pediatric Surgery·B W DaviesM D Stringer
Oct 22, 2008·The Journal of Urology·Charles D Scales, John S Wiener
Apr 29, 1998·The Journal of Urology·J N'DowD E Neal

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