Long-Term Outcome of Fetuses with Soft Marker and Without Genetic or Structural Abnormality

Journal of Obstetrics and Gynaecology of India
Migraci TosunGonul Ogur

Abstract

To determine long-term outcome of infants with isolated or multiple soft markers but no structural or chromosomal abnormalities. A retrospective study of 78 pregnant women who were referred for amniocentesis and found to have soft markers including echogenic intracardiac focus/foci (EIF), echogenic bowel (EB), unilateral or bilateral choroid plexus cysts, (UCPCs or BCPCs) mild pyelectasis and single umbilical artery but no structural anomalies and outcomes of the liveborns with a 4- to 9-year follow-up was conducted. Among 28 fetuses with EIF, allergic asthma and epilepsy were diagnosed in two liveborns. We followed up nine pregnancies with EB, epilepsy was present in one case. Allergic asthma was detected in both UCPCs and BCPCs, whereas epilepsy and attention-deficit/hyperactivity disorder (ADHD) were diagnosed in two liveborns with BCPCs. Twelve liveborns with multiple soft markers were evaluated; no pathology was detected in most of them except one case of allergic asthma, one case of hearing impairment and one case of ADHD. This study shows longer-term favorable outcomes of the liveborns with isolated or multiple soft markers without any aneuploidy and may provide insight into this debated point.

References

Dec 19, 2007·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·T DagklisK H Nicolaides
Jun 23, 2009·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·P MassonP Quetin
Sep 3, 2010·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Zehra Sema OzkanHüseyin Yüce
Sep 18, 2010·Journal of Clinical Ultrasound : JCU·Geetika GuptaShubha R Phadke
May 17, 2012·Prenatal Diagnosis·Esha SahaLorin Lakasing
Jun 20, 2012·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Shafia ShakoorShama Munim
Sep 20, 2012·Archives of Disease in Childhood. Fetal and Neonatal Edition·Hannah D BuiterArend F Bos
May 29, 2013·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·K M Orzechowski, V Berghella
Jan 18, 2014·Acta Obstetricia Et Gynecologica Scandinavica·Annika AhmanPeter Lindgren
Mar 7, 2014·Prenatal Diagnosis·Eran AshwalYariv Yogev
Mar 29, 2014·World Journal of Pediatrics : WJP·Jose Vicente Arcos-MachancosesMáximo Vento
Jul 16, 2014·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·E Araujo JúniorF da Silva Costa
Nov 12, 2014·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Atalay EkinMehmet Ozeren
Feb 18, 2015·Current Opinion in Obstetrics & Gynecology·Vedran Stefanovic
Mar 20, 2015·Journal of the Turkish German Gynecological Association·Fırat TülekFeride Söylemez

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