Long-term outcome of postmenopausal women with non-atypical endometrial hyperplasia on endometrial sampling.

Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology
O RotenbergP Dar

Abstract

To assess the long-term outcome of postmenopausal women diagnosed with non-atypical endometrial hyperplasia (NEH). This was a retrospective study of women aged 55 or older who underwent endometrial sampling in our academic medical center between 1997 and 2008. Women who had a current or recent (< 2 years) histological diagnosis of NEH were included in the study group and were compared with those diagnosed with atrophic endometrium (AE). Outcome data were obtained until February 2018. The main outcomes were risk of progression to endometrial carcinoma and risk of persistence, recurrence or new development of endometrial hyperplasia (EH) ('persistent EH'). Logistic regression analysis was used to identify covariates that were independent risk factors for progression to endometrial cancer or persistent EH. During the study period, 1808 women aged 55 or older underwent endometrial sampling. The median surveillance time was 10.0 years. Seventy-two women were found to have a current or recent diagnosis of NEH and were compared with 722 women with AE. When compared to women with AE, women with NEH had significantly higher body mass index (33.9 kg/m2 vs 30.6 kg/m2 ; P = 0.01), greater endometrial thickness (10.00 mm vs 6.00 mm; P = 0.0...Continue Reading

References

Jan 1, 1986·Acta Obstetricia Et Gynecologica Scandinavica·A LidorM P David
Jun 1, 1997·The Journal of Obstetrics and Gynaecology Research·N TerakawaM Furusato
Jun 21, 2001·Archives of Gynecology and Obstetrics·T TabataY Nose
Mar 15, 2005·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·M Moodley, C Roberts
Mar 19, 2008·The American Journal of Surgical Pathology·Kimberly H AllisonRochelle L Garcia
Mar 26, 2009·Journal of the National Cancer Institute·Nadia HowladerBrenda K Edwards
Jan 13, 2010·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·James V LaceyBryan Langholz
Dec 27, 2011·Gynecologic Oncology·Sofie Leisby AntonsenClaus Høgdall
Jul 3, 2013·Obstetrics and Gynecology·Ioannis D GallosJanesh K Gupta
Apr 1, 2014·Archives of Pathology & Laboratory Medicine·Richard A Owings, Charles M Quick
Mar 24, 2015·Geburtshilfe und Frauenheilkunde·G EmonsUNKNOWN Uterus commission of the Gynecological Oncology Working Group (AGO)
Dec 3, 2015·BJOG : an International Journal of Obstetrics and Gynaecology·A ØrboB Straume
Oct 30, 2016·American Journal of Obstetrics and Gynecology·Michelle R WiseCynthia M Farquhar

❮ Previous
Next ❯

Citations

Sep 19, 2020·The Journal of Obstetrics and Gynaecology Research·Nara LeeYong Beom Kim
Jul 9, 2020·American Journal of Obstetrics and Gynecology·Ohad RotenbergPe'er Dar

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cancer Imaging

Imaging techniques, including CT and MR, have become essential to tumor detection, diagnosis, and monitoring. Here is the latest research on cancer imaging.