Long-Term Outcome of Transcatheter Device Closure of Perimembranous Ventricular Septal Defects

Frontiers in Pediatrics
Krishna D MandalYusheng Pang

Abstract

Background: Ventricular septal defect is a common congenital heart defect. Transcatheter closure of perimembranous ventricular septal defect (pmVSD) is an effective method alternative to surgical closure. The aim of the study is to evaluate the procedural result, early and long-term follow-up outcome of transcatheter closure of pmVSD. Methods: From January 2005 to December 2016, we retrospectively identified the patients who underwent transcatheter device closure of pmVSD. All patients underwent transthoracic echocardiography (TTE) and electrocardiogram (ECG) before and after the procedure. Follow-up evaluation was done at 1, 3, 6, 12 months and yearly thereafter with TTE and ECG. Results: Total 186 patients (95 male, 91 female) had catheter-based intervention of pmVSD. The mean age at the time of procedure was 5.4 ± 2.8 years (range 2~14 years) and the mean weight was 18.1 ± 6.7 kg (range 10.5~43 kg). The mean size of the implanted device was 8.4 ± 2.1 mm (range 5~16 mm). The device was successfully implanted in 180 patients (96.8%). Immediate post-procedural echocardiography showed complete occlusion in all but one patient had trivial residual shunt. Total early adverse events occurred in 16 patients (8.9%). Only in two patie...Continue Reading

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Citations

May 16, 2019·World Journal for Pediatric & Congenital Heart Surgery·Ajith Ananthakrishna PillaiVidhyakar Rangaswamy Balasubramonian
Jul 31, 2018·Annals of Thoracic and Cardiovascular Surgery : Official Journal of the Association of Thoracic and Cardiovascular Surgeons of Asia·Guan-Hua FangLiang-Wan Chen
Nov 1, 2020·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Rainer Kozlik-FeldmannThomas Meinertz
May 9, 2021·Acta Biomaterialia·Cheng LinJinsong Leng
Jul 10, 2021·Cardiology Research and Practice·Hongyan ZhengZhiwei Zhang

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Methods Mentioned

BETA
sedation
pharmacotherapy

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SPSS

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