Long-term outcomes after endoscopic ultrasound-guided ablation of pancreatic cysts

Endoscopy
Jun-Ho ChoiMyung-Hwan Kim

Abstract

Background and study aims The aim of this study was to investigate the long-term outcomes after endoscopic ultrasound (EUS)-guided pancreatic cyst ablation. Patients and methods In a single-center, prospective study, 164 patients with pancreatic cysts underwent EUS-guided cyst ablation using ethanol with paclitaxel. The inclusion criteria were as follows: unilocular or oligolocular cysts; clinically indeterminate cysts that required EUS fine-needle aspiration; and/or cysts that grew during the observation period. Treatment response was classified as complete resolution, partial resolution, or persistent cyst, with < 5 %, 5 % - 25 %, and 25 % of the original cyst volume, respectively. Results The median largest diameter of the cyst was 32 mm and the median volume was 17.1 mL. Based on cyst fluid analysis there were 71 mucinous cystic neoplasms, 16 serous cystic neoplasms, 11 intraductal papillary mucinous neoplasms, 3 pseudocysts, and 63 indeterminate cysts. Sixteen treated patients (9.8 %) had adverse events (1 severe, 4 moderate, and 11 mild). Treatment response was as follows: complete resolution in 114 (72.2 %), partial resolution in 31 (19.6 %), and persistent cysts in 13 (8.2 %). Twelve of the 13 patients with persistent c...Continue Reading

Citations

Mar 27, 2018·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Jun-Ho ChoiSung Koo Lee
Apr 25, 2019·Current Gastroenterology Reports·Matthew T MoyerJohn M DeWitt
Jan 23, 2019·Clinical Endoscopy·Zaheer Nabi, D Nageshwar Reddy
May 16, 2019·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Gian Eugenio TontiniLuca Elli
Sep 19, 2019·Nature Reviews. Gastroenterology & Hepatology·Nadine C M van HuijgevoortMarc G Besselink
Jul 21, 2020·World Journal of Gastroenterology : WJG·Chen DuXiu-Xue Feng
Jan 25, 2018·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Sang Hyub Lee
Sep 10, 2019·European Journal of Gastroenterology & Hepatology·Chen DuEnqiang Linghu
Nov 11, 2019·Hepatobiliary & Pancreatic Diseases International : HBPD INT·Elia Armellini
Apr 4, 2021·Journal of Clinical Medicine·Margaret G Keane, Elham Afghani
Apr 5, 2021·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Courtney LesterMatthew T Moyer
Aug 13, 2021·Digestive Diseases and Sciences·Andrew Canakis, Linda S Lee
Dec 1, 2020·GE Portuguese Journal of Gastroenterology·Miguel BispoNuno Nunes

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