Long-term outcomes following Gamma Knife radiosurgery for small, newly diagnosed meningiomas

Clinical Neurology and Neurosurgery
Seungjoo LeeJeong Hoon Kim

Abstract

Although stereotactic radiosurgery were established as an effective treatment modality for intracranial meningiomas, there have been no comprehensive studies focused on long-term outcomes and histologic results for purely small-sized meningiomas after radiosurgery. Therefore, we investigated long-term outcomes and histology of small-sized meningiomas after radiosurgery. The authors reviewed the data retrospectively of a total of 920 patients treated with single-session Gamma Knife radiosurgery with intracranial meningioma (Radiosurgery center, Asan Medical Center). After stratifying meningiomas by size, it was defined as small-sized meningiomas less than 1000 mm(3) in tumor volume. The patients with newly diagnosed small-sized meningiomas were enrolled in this study (113 patients). All patients had a minimum follow up of 12 months (12-120 months), clinical symptoms and brain MRI were checked by neurosurgeons. When the tumors grew readily with newly developed neurologic symptoms, microsurgical resection was performed. Histologic analysis was done with resected tumors by neuropathologists. Among 113 patients, 9 patients (7.9%) showed the increased tumors with clinical symptoms after radiosurgery, followed by microsurgical resecti...Continue Reading

References

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