Long term outcomes in men screened for abdominal aortic aneurysm: prospective cohort study.

BMJ : British Medical Journal
John L DuncanDavid J Godden

Abstract

To determine whether there is a relation between aortic diameter and morbidity and mortality in men screened for abdominal aortic aneurysm. Prospective cohort study. Highland and Western Isles (a large, sparsely populated area of Scotland). 8146 men aged 65-74. Morbidity and mortality in relation to presence of abdominal aortic aneurysm and three categories of aortic diameter (≤ 24 mm, 25-29 mm, and ≥ 30 mm). When screened, 414 men (5.1%) had an aneurysm (diameter ≥ 30 mm), 669 (8.2%) an aortic diameter of 25-29 mm, and 7063 (86.7%) an aortic diameter of ≤ 24 mm. The cohort was followed up for a median of 7.4 (interquartile range 6.9-8.2) years. Mortality was significantly associated with aortic diameter: 512 (7.2%) men in the ≤ 24 mm group died compared with 69 (10.3%) in the 25-29 mm group and 73 (17.6%) in the ≥ 30 mm group. The mortality risk in men with an aneurysm or with an aorta measuring 25-29 mm was significantly higher than in men with an aorta of ≤ 24 mm. The increased mortality risk in the 25-29 mm group was reduced when taking confounders such as smoking and known heart disease into account. After adjustment, compared with men with an aortic diameter of ≤ 24 mm, the risk of hospital admission for cardiovascular di...Continue Reading

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Citations

Jan 8, 2013·The Surgeon : Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland·Kathryn J GriffinPaul D Baxter
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