Long Term Outcomes of Patients Treated With Transcatheter Aortic Valve Implantation.

The American Journal of Cardiology
Nili Schamroth PravdaRan Kornowski

Abstract

Transcatheter aortic-valve implantation (TAVI) is an established treatment option in patients with severe symptomatic aortic stenosis. Intermediate and long-term follow up data of these patients is limited. Data was taken from a large all-comer single center prospective registry (2008 to 2019). The primary end point was all-cause mortality. The secondary endpoints were long-term valve hemodynamic performance; paravalvular leak (PVL) at 5-year follow-up. We also report on temporal trends in this cohort. Our cohort included 998 patients with a mean age of 82.3 ± 7.2 years and 52.2% females. TAVI was performed via the transfemoral, trans-apical, subclavian and other access routes in 93.9%, 3.6%, 2.5%, and 0.6% of patients, respectively. A self-expandable device was used in 69.4% of cases, balloon expandable device in 28.1% and in 2.5% other devices. The cumulative risk for all-cause mortality at 5 years was 43.4% (95% CI 39.1 to 47.7). The immediate and long-term valve gradients were low and maintained. On durability analysis at 5 years, severe structural valve deterioration was present in 1.6% of cases. At 5-year follow-up, PVL was moderate in 3.3% and no patients has severe PVL. On temporal trends analysis, we found that the pro...Continue Reading

References

Oct 23, 2012·The Journal of Thoracic and Cardiovascular Surgery·A Pieter KappeteinUNKNOWN Valve Academic Research Consortium-2
Dec 17, 2014·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Robert M A van der BoonFrits W Prinzen
Apr 5, 2016·The New England Journal of Medicine·Martin B LeonUNKNOWN PARTNER 2 Investigators
Apr 14, 2016·Journal of Renal Injury Prevention·Wisit CheungpasitpornKianoush Kashani
Mar 18, 2017·The New England Journal of Medicine·Michael J ReardonUNKNOWN SURTAVI Investigators
Jul 1, 2017·Journal of the American College of Cardiology·Vincent AuffretUNKNOWN FRANCE TAVI Investigators
Aug 25, 2017·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Ahmad AlkhalilGuilherme F Attizzani
Feb 9, 2019·Journal of the American College of Cardiology·Daniel J BlackmanDavid Hildick-Smith
Feb 9, 2019·Journal of the American College of Cardiology·Lars SøndergaardHans Gustav Hørsted Thyregod
Mar 19, 2019·The New England Journal of Medicine·Michael J MackUNKNOWN PARTNER 3 Investigators
Apr 5, 2019·The New England Journal of Medicine·Sreekanth VemulapalliJoseph E Bavaria
Jul 10, 2019·Circulation. Cardiovascular Interventions·Marco BarbantiUNKNOWN OBSERVANT Research Group
Nov 2, 2019·Journal of the American Heart Association·Amgad MentiasMary S Vaughan Sarrazin
Jan 30, 2020·The New England Journal of Medicine·Raj R MakkarUNKNOWN PARTNER 2 Investigators

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