Long-term outcomes using the stentless LivaNova-Sorin Pericarbon Freedom™ valve after aortic valve replacement

Interactive Cardiovascular and Thoracic Surgery
Guglielmo StefanelliLuca Weltert

Abstract

Information on the long-term safety, efficacy and durability of third-generation stentless aortic valves is lacking. In this single-centre, single-surgeon retrospective observational study, between 2003 and 2015, consecutive, non-selected aortic valve replacement (AVR) patients were implanted with the LivaNova-Sorin Pericarbon Freedom™, a third-generation stentless aortic xenograft. Changes in clinical and echocardiographic parameters were examined, as were mortality, structural valve deterioration and reoperation, according to age at 5, 10 and 14 years. The mean logistic EuroSCORE was 8.5% in 22 AVR patients (mean age 68.3 years; range 15-89 years). Many patients [n = 139 (43%)] underwent a concomitant procedure. Before AVR, 68.0% of patients were in New York Heart Association (NYHA) Class I or II, and at discharge, mean gradient was 10.0 ± 4.3 mmHg. Follow-up lasted up to 8.9 ± 2.8 years. At the last follow-up, 95.6% of patients were in New York Heart Association Class I or II, the mean gradient was 8.0 ± 3.5 mmHg (P < 0.001) and reduction in interventricular septum thickness and improvement of ejection fraction were significant (both P < 0.001). Early 30-day in-hospital mortality was 1.6% overall and 0% in the AVR-only popul...Continue Reading

References

Mar 1, 1990·The Annals of Thoracic Surgery·M AmidiM S Melhem
Mar 20, 2002·The Annals of Thoracic Surgery·Gideon CohenBernard S Goldman
Jul 23, 2005·The Thoracic and Cardiovascular Surgeon·S BeholzW Konertz
Mar 23, 2006·Asian Cardiovascular & Thoracic Annals·Sven BeholzWolfgang Konertz
Apr 4, 2006·The Journal of Thoracic and Cardiovascular Surgery·Farhad BakhtiaryPeter Kleine
Feb 20, 2007·Journal of the American College of Cardiology·Farhad BakhtiaryPeter Kleine
Jul 31, 2007·The Journal of Thoracic and Cardiovascular Surgery·Augusto D'OnofrioAlessandro Fabbri
May 29, 2008·Interactive Cardiovascular and Thoracic Surgery·Can YerebakanAndreas Liebold
Jun 27, 2008·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Michele MusciRoland Hetzer
Oct 10, 2008·Interactive Cardiovascular and Thoracic Surgery·Lutz HilkerLothar Eckel
Nov 26, 2009·The Annals of Thoracic Surgery·Helmut Gulbins, Hermann Reichenspurner
Oct 23, 2010·The Journal of Thoracic and Cardiovascular Surgery·K M John ChanGilles D Dreyfus
Jun 5, 2012·The International Journal of Artificial Organs·Aldo D MilanoAlessandro Mazzucco
Jul 10, 2012·The Annals of Thoracic Surgery·Vito Giovanni RuggieriAlain Leguerrier
Jun 5, 2013·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Tarun ChakravartyRaj Makkar
Mar 4, 2015·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Sandro SpongaUgolino Livi
Jul 19, 2015·The Annals of Thoracic Surgery·Thierry BourguignonMichel Aupart
Jun 4, 2016·Interactive Cardiovascular and Thoracic Surgery·Guglielmo StefanelliAndrea Barbieri

❮ Previous
Next ❯

Citations

Sep 1, 2020·Innovations : Technology and Techniques in Cardiothoracic and Vascular Surgery·Guglielmo StefanelliLuca Weltert
Jul 7, 2020·Innovations : Technology and Techniques in Cardiothoracic and Vascular Surgery·Guglielmo StefanelliLuca Weltert
Nov 19, 2020·Cardiovascular Engineering and Technology·Kinga DawidowskaMagdalena Kołaczkowska
Oct 13, 2020·The Annals of Thoracic Surgery·Guglielmo StefanelliLuca Weltert

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The Journal of Heart Valve Disease
Hasim UstunsoyOzerdem Ozcaliskan
European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery
M VrandecicE Vrandecic
© 2022 Meta ULC. All rights reserved