Long-Term Oxygen Therapy in COPD Patients Who Do Not Meet the Actual Recommendations

COPD
Begum Ergan, Stefano Nava

Abstract

Chronic respiratory failure due to chronic obstructive pulmonary disease (COPD) is an increasing problem worldwide. Many patients with severe COPD develop hypoxemic respiratory failure during the natural progression of disease. Long-term oxygen therapy (LTOT) is a well-established supportive treatment for COPD and has been shown to improve survival in patients who develop chronic hypoxemic respiratory failure. The degree of hypoxemia is severe when partial pressure of oxygen in arterial blood (PaO2) is ≤55 mmHg and moderate if PaO2is between 56 and 69 mmHg. Although current guidelines consider LTOT only in patients with severe resting hypoxemia, many COPD patients with moderate to severe disease experience moderate hypoxemia at rest or during special circumstances, such as while sleeping or exercising. The efficacy of LTOT in these patients who do not meet the actual recommendations is still a matter of debate, and extensive research is still ongoing to understand the possible benefits of LTOT for survival and/or functional outcomes such as the sensation of dyspnea, exacerbation frequency, hospitalizations, exercise capacity, and quality of life. Despite its frequent use, the administration of "palliative" oxygen does not seem ...Continue Reading

References

Jul 1, 1987·The American Review of Respiratory Disease·S R SelingerJ R Michael
Nov 1, 1995·American Journal of Respiratory and Critical Care Medicine·C F McDonaldC E Barter
Jun 1, 1997·The European Respiratory Journal·J M RooyackersH T Folgering
Aug 1, 1997·The European Respiratory Journal·A ChaouatJ Moutinho dos Santos
Jan 5, 1999·American Journal of Respiratory and Critical Care Medicine·H F BeckerC E Sullivan
Dec 22, 1999·The European Respiratory Journal·A ChaouatJ Moutinho dos Santos
Aug 8, 2001·The European Respiratory Journal·A ChaouatJ Moutinho dos Santos
Aug 3, 2002·American Journal of Respiratory and Critical Care Medicine·Steven M ScharfUNKNOWN National Emphysema Treatment Trial (NETT) Group
Sep 6, 2002·The European Respiratory Journal·T EatonK Whyte
Jul 19, 2003·American Journal of Respiratory and Critical Care Medicine·Margareta EmtnerRichard Casaburi
Feb 13, 2004·Respiratory Medicine·Sara BoothUNKNOWN Expert Working Group of the Scientific Committee of the Association of Palliative Medicine
Apr 10, 2004·Respiratory Medicine·T EatonJ Kolbe
Aug 19, 2004·Respiration; International Review of Thoracic Diseases·P HaidlD Köhler
Nov 11, 2005·Chronic Respiratory Disease·T J RingbaekP Lange
Mar 27, 2007·Respiratory Medicine·Nicolino Ambrosino, Anita Simonds
Apr 21, 2007·American Journal of Respiratory and Critical Care Medicine·Mika L NonoyamaRoger S Goldstein
May 6, 2008·Proceedings of the American Thoracic Society·Victor KimAmir Sharafkhaneh
Sep 29, 2009·Journal of Critical Care·Ravindranath TiruvoipatiJohn Botha
Feb 27, 2010·Canadian Respiratory Journal : Journal of the Canadian Thoracic Society·Nha VoducShawn D Aaron
Jan 11, 2011·American Journal of Respiratory and Critical Care Medicine·Magnus P EkströmKerstin E Ström
Mar 15, 2011·Respiratory Medicine·Deog Kyeom KimCraig P Hersh
Apr 19, 2011·Respiratory Care·Rachael L ParkeShay P McGuinness
Apr 19, 2011·Canadian Respiratory Journal : Journal of the Canadian Thoracic Society·Darcy D MarciniukUNKNOWN Canadian Thoracic Society COPD Committee Dyspnea Expert Working Group
May 3, 2011·Current Opinion in Supportive and Palliative Care·Patricia M Davidson, Miriam J Johnson
May 13, 2011·Respiratory Medicine·Yves LacasseFrançois Maltais
May 25, 2011·Respiratory Care·Ignacio Garcia-TalaveraJuan Abreu
Jul 17, 2012·Respiratory Medicine·Monica Linea VoldHasse Melbye

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Citations

Sep 20, 2018·Respirology : Official Journal of the Asian Pacific Society of Respirology·Kiyoshi UemasuToyohiro Hirai
Jun 15, 2018·European Respiratory Review : an Official Journal of the European Respiratory Society·Begum ErganStefano Nava
Feb 2, 2019·Respiratory Medicine·Marcello BosiVenerino Poletti
Mar 12, 2021·Frontiers in Medicine·Konstantinos BitosKonrad E Bloch
Apr 30, 2021·Frontiers in Cardiovascular Medicine·Srikanth KarnatiSüleyman Ergün
Sep 17, 2021·Monaldi Archives for Chest Disease = Archivio Monaldi Per Le Malattie Del Torace·Biswajit MaharanaShreeji Kadakia

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