Long-term Patient-Reported Outcomes in Older Breast Cancer Survivors: A Population-Based Survey Study

International Journal of Radiation Oncology, Biology, Physics
Cameron W SwanickBenjamin D Smith

Abstract

For older women with breast cancer, local therapy options may include lumpectomy plus whole-breast irradiation (Lump + WBI), lumpectomy plus brachytherapy (Lump + Brachy), lumpectomy alone (Lump alone), mastectomy without radiation therapy (Mast alone), and mastectomy plus radiation therapy (Mast + RT). We surveyed a population-based cohort of older breast cancer survivors to assess the association of local therapy with long-term quality-of-life outcomes. We used nationally comprehensive Medicare claims to identify women aged ≥67 years in whom nonmetastatic breast cancer was diagnosed in 2009, who were treated with 1 of the 5 aforementioned treatment options, and who were still alive in 2015. From this cohort, 1650 patients (330 patients per treatment) were randomly selected. A survey that included the CanSORT (Cancer Surveillance and Outcomes Research Team) Satisfaction with Breast Cosmetic Outcome, BREAST-Q, Decisional Regret Scale, and EQ-5D-3L was mailed to potential participants. We used multivariable linear regression to assess associations between local therapy and outcomes after adjusting for patient, disease, and treatment covariates. Among the 489 women who returned the surveys (30% response rate), the median age at d...Continue Reading

Citations

Dec 7, 2018·Breast Cancer Research and Treatment·Steven S CoughlinJudith Anglin
Jan 21, 2021·Journal of Cancer Survivorship : Research and Practice·Hjelmér IdaNenonen Hannah
Apr 15, 2021·Journal of Cancer Survivorship : Research and Practice·J David BeattyRuth Etzioni
Jul 4, 2021·Breast Cancer Research and Treatment·Daphne H M JacobsHelena M Verkooijen

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