Long-term patient survival after the surgical treatment of bone and soft-tissue metastases from renal cell carcinoma

The Bone & Joint Journal
Takashi HiguchiHiroyuki Tsuchiya

Abstract

The aims of this study were to evaluate the long-term outcome of surgery for bone or soft-tissue metastases from renal cell carcinoma (RCC) and to determine factors that affect prognosis. Between 1993 and 2014, 58 patients underwent surgery for bone or soft-tissue metastases from RCC at our hospital. There were 46 men and 12 women with a mean age of 60 years (25 to 84). The mean follow-up period was 52 months (1 to 257). The surgical sites included the spine (33 patients), appendicular skeleton (ten patients), pelvis (eight patients), thorax (four patients), and soft tissue (three patients). The surgical procedures were en bloc metastasectomy in 46 patients (including 33 patients of total en bloc spondylectomy (TES)) and intralesional curettage in 12 patients. These patients were retrospectively evaluated for factors associated with prognosis. The one-, three-, five-, ten-, and 15-year overall survival (OS) rates were 89%, 75%, 62%, 48%, and 25%, respectively. The median survival time (MST) was 127 months for en bloc metastasectomy and 54 months for intralesional curettage and bone grafting. The median survival time was 127 months for the spine, 140 months for lesions of the appendicular skeleton, and 54 months for the pelvis. ...Continue Reading

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Citations

May 29, 2020·Current Opinion in Urology·Sara OmidMesut Remzi
Aug 15, 2020·Asian Spine Journal·Sam Yeol ChangBong-Soon Chang
Mar 3, 2020·The Bone & Joint Journal·Atsushi TanakaMitsuru Takahashi
Dec 8, 2020·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Keyi WangBo Peng
Apr 7, 2021·Japanese Journal of Clinical Oncology·Katsuhiro HayashiAkira Kawai
Aug 9, 2020·Orthopaedics & Traumatology, Surgery & Research : OTSR·Pierre LavignacUNKNOWN Members of the S.O.F.C.O.T.
Aug 10, 2020·Orthopaedics & Traumatology, Surgery & Research : OTSR·Aymeric de GeyerUNKNOWN SoFCOT
Apr 11, 2020·Orthopaedics & Traumatology, Surgery & Research : OTSR·Paul BonnevialleUNKNOWN SoFCOT members
Oct 6, 2021·Current Opinion in Supportive and Palliative Care·Megan PruntySarah P Psutka
Dec 27, 2021·Orthopaedics & Traumatology, Surgery & Research : OTSR·Charlie BouthorsUNKNOWN members of the SoFCOT

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