Long-term potentiation in rat prefrontal slices facilitated by phased application of dopamine

European Journal of Pharmacology
O BlondS Otani

Abstract

We have previously shown that coupling bath application of dopamine with 50 Hz tetani induces long-term depression in rat prefrontal slices [Neuroscience 85 (1998) 669]. Here, we report a reliable protocol for inducing long-term potentiation in the same preparation. Long-term potentiation was induced by the same dopamine-tetani coupling protocol when the coupling was preceded (approximately 30 min) by a single bath application of dopamine. We suggest that metaplastic processes triggered by the first application of dopamine might underlie the LTP induction.

Citations

Jul 10, 2004·Journal of Physiology, Paris·Satoru Otani
Jul 26, 2003·Progress in Neurobiology·Thérèse M Jay
Dec 12, 2002·Biological Reviews of the Cambridge Philosophical Society·Satoru Otani
Jul 19, 2005·Behavioral and Brain Functions : BBF·Vivienne A RussellEspen Borgå Johansen
Nov 13, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Tai-Xiang XuWei-Dong Yao
Feb 26, 2004·Proceedings of the National Academy of Sciences of the United States of America·Yan-You HuangEric R Kandel
Oct 1, 2014·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Timothy J Buschman, Earl K Miller
Dec 20, 2003·Annals of the New York Academy of Sciences·Marina E WolfXiu Sun
Oct 7, 2004·Neuropharmacology·Marina E WolfSteven Z Chao
Sep 24, 2004·Progress in Neurobiology·Jeremy K Seamans, Charles R Yang
Jul 15, 2015·Annual Review of Neuroscience·Beatriz LunaRajpreet Chahal
Oct 18, 2002·Neuron·Wolfram Schultz
Feb 24, 2011·The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry·Charlotte J Stagg, Michael A Nitsche
Apr 16, 2004·Journal of Neurophysiology·Yves Manunta, Jean-Marc Edeline
Jun 20, 2008·Reviews in the Neurosciences·Min Whan JungJeansok John Kim
Jul 12, 2017·Frontiers in Computational Neuroscience·Raphaël Holca-LamarreKlaus Obermayer

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