Long-term prognosis for endocapillary glomerulonephritis of poststreptococcal type in children and adults

Nephron
W VoglA Bohle

Abstract

The long-term clinical course of sporadic, acute endocapillary glomerulonephritis of poststreptococcal type is reported. In all cases, the diagnosis was established by renal biopsies and in most cases by clinical tests. The study is based on retrospective/prospective data from 36 children and 101 adults in the Federal Republic of Germany, Luxemburg, and Austria. In 72 patients (21 children, 51 adults) the disease course was clinically followed over periods of 2-13 years (clinical features: blood pressure, serum creatinine, proteinuria, hematuria). In this group, the number of clinical recoveries (i.e., all features within strictly defined normal ranges) increased with increasing length of observation. Children showed more rapid clinical recovery. 29% of the children and 41% of the adults showed no clinical recovery. Out of all 137 patients, 3 progressed to chronic renal failure, and 4 other patients died. Cases with an initial nephrotic syndrome had a significantly poorer long-term prognosis (p less than 0.005). Initial elevation of serum creatinine concentration due to acute renal failure did not influence the long-term prognosis. Our results indicate that the acute endocapillary glomerulonephritis of poststreptococcal type ha...Continue Reading

Citations

Oct 1, 1988·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·G ClarkL A Comley
Jan 1, 1995·International Urology and Nephrology·M WashioS Fujimi
Dec 20, 2008·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·William WongJonathan Zwi
Jul 20, 2010·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Mei-Ching YuWen-Hung Huang
Aug 12, 2009·International Urology and Nephrology·Yao-Ko Wen
Jun 1, 1996·Disease-a-month : DM·R J Glassock, A H Cohen
Apr 23, 2009·Nature Reviews. Nephrology·Talerngsak KanjanabuchSomchai Eiam-Ong
Jul 27, 2001·Pediatrics International : Official Journal of the Japan Pediatric Society·T KasaharaM Uchiyama
May 28, 2005·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Ricardo Sesso, Sergio Wyton L Pinto
Jul 15, 2005·Kidney International. Supplement·Ricardo SessoL Pinto
Aug 14, 2012·Advances in Anatomic Pathology·Neeraja Kambham
Dec 4, 1990·Klinische Wochenschrift·J A FuhrerR A Streuli
Apr 10, 2012·Néphrologie & thérapeutique·Benyounès RamdaniGhizlane Medkouri
Aug 10, 2006·Néphrologie & thérapeutique·Hédi Ben MaïzAdel Kheder
May 12, 2015·PloS One·Sergio Wyton L PintoRicardo Sesso
Feb 7, 2007·International Review of Cytology·Ian A Darby, Tim D Hewitson
Sep 12, 2017·Paediatrics and International Child Health·Ramnath Balasubramanian, Stephen D Marks
Jan 26, 2007·Pediatrics International : Official Journal of the Japan Pediatric Society·Kazuhide SuyamaHitoshi Suzuki
Aug 1, 2008·Journal of the American Society of Nephrology : JASN·Bernardo Rodriguez-Iturbe, James M Musser
Aug 11, 2019·Nature Reviews. Nephrology·Anjali A SatoskarTibor Nadasdy

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.