PMID: 11917199Mar 28, 2002Paper

Long-term prognostic value of dipyridamole echocardiography in vascular surgery: a large-scale multicenter study

Coronary Artery Disease
Rosa SicariEPIC (Echo Persantine International Cooperative) Study Group

Abstract

Late cardiac events after non-cardiac major vascular surgery are an important cause of morbidity and mortality. The aim of the present study was to assess the value of a preoperative dipyridamole echocardiography test (up to 0.84 mg/kg over 10 min) in predicting late cardiac events in survivors of major non-cardiac vascular surgery. Large-scale, multicenter, prospective, observational study design. Two hundred and seventy-six patients (mean age 66 +/- 9 years) were studied prior to vascular surgery by dipyridamole stress echocardiography in four different centres. All patients underwent preoperative clinical risk assessment according to the American Heart Association guidelines. All underwent dipyridamole stress echocardiography according to standard high-dose protocol. No major complications occurred during dipyridamole stress echocardiography. Sixty-three patients (23%) had a positive test. Patients were followed up for a median of 20 months. Cardiac events occurred in 43 patients (16%): five deaths, 18 myocardial infarctions and 20 cases of unstable angina. The difference between wall-motion score index (WMSI) at rest and peak stress (delta WMSI), using multivariate analysis, was an independent predictor of late cardiac deat...Continue Reading

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Citations

Jun 27, 2008·European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology·Rosa SicariUNKNOWN European Association of Echocardiography
Mar 23, 2017·Cardiovascular Ultrasound·Rosa Sicari, Lauro Cortigiani

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