Long-term quality of life after posterior cervical foraminotomy for radiculopathy

Clinical Neurology and Neurosurgery
Ryan W FaughtFrederick A Simeone

Abstract

Cervical radiculopathy may cause symptoms and loss of function that can lead to a significant reduction in health related quality of life (HRQOL). As part of a comprehensive review of long-term outcomes, we examined HRQOL in a large cohort of patients undergoing posterior cervical foraminotomy (FOR) for radiculopathy. 338 patients who underwent FOR between 1990 and 2009 participated in a telephone interview designed to measure symptomatic and functional improvements following surgery. We also administered the EQ-5D, a standardized tool for assessing HRQOL. We analyzed this data for associations between patient and treatment characteristics, improvements in symptoms and function, and HRQOL as measured by the EQ-5D. Mean follow-up was 10.0 years. The average EQ-5D at follow-up was 0.81±0.18, and improvements in pain, weakness and function as well as ability to return to work correlated with improved EQ-5D score (p<0.0001). There was no correlation between length of follow-up and EQ-5D score (p=0.980). Additionally, there was no difference between mean EQ-5D score for soft disc versus osteophyte pathology (0.84 versus 0.81, p=0.21). These data provide evidence that FOR for cervical radiculopathy is associated with improved HRQOL a...Continue Reading

References

May 9, 1966·JAMA : the Journal of the American Medical Association·W B Scoville
Jan 1, 1996·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·K Bush, S Hillier
Nov 21, 1997·Medical Care·P Dolan
Sep 16, 2003·Spine·Scott D DaffnerTodd J Albert
Nov 1, 2003·The Spine Journal : Official Journal of the North American Spine Society·Nobusuke KobayashiKiyoshi Matusmoto
Feb 5, 2009·The Journal of Bone and Joint Surgery. British Volume·K-A JanssonP Blomqvist
May 4, 2010·Spine·Philipp BeckerMichael Ogon
Jul 16, 2010·BMJ : British Medical Journal·Ioannis P FouyasIoannis Nikolaidis
Mar 25, 2011·Journal of Spinal Disorders & Techniques·Andrew J SchoenfeldPedro M Caram
Jul 4, 2012·Neurosurgical Focus·Matthew R SanbornSherman C Stein

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Citations

Jun 3, 2016·Current Reviews in Musculoskeletal Medicine·Sravisht Iyer, Han Jo Kim
Feb 15, 2019·Clinical Spine Surgery : a Spine Publication·Jung K MokSheeraz Qureshi
Dec 30, 2020·Asian Spine Journal·Kyung-Chung KangJung-Hee Lee
May 31, 2021·Clinics in Sports Medicine·Robert G Watkins, Robert G Watkins

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