Long-term quality of life associated with early surgical complications in patients with ulcerative colitis after ileal pouch-anal anastomosis: A single-center retrospective study

International Journal of Surgery
Weimin XuPeng Du

Abstract

Ileal pouch-anal anastomosis (IPAA) is recommended for patients with ulcerative colitis (UC) in terms of surgical treatment. Measuring surgical complications of IPAA and long-term quality of life (QOL) are important to achieve an acceptable risk/benefit ratio for patients with UC. Patients with UC who underwent total proctocolectomy (TPC) with IPAA from February 2008 to July 2016 at our institute were included. Early surgical complications were defined as mechanical/infectious events within one month after IPAA. Assessment of QOL was performed using the Cleveland Global Quality of Life instrument (CGQL), with 50% improvement as a cut-off value. Demographic and clinical variables were compared with univariable analysis and step-wise logistic regression models were also performed. A total of 58 eligible patients had a median follow-up time of 78.5 months [interquartile range (IQR), 34.4-92.8] from February2008 to March 2017, including 25 cases (43.1%) developed early surgical complications. Age at pouch surgery and excessive blood loss were risk factors associated with early surgical complications (p < 0.05). In multivariate analysis, older age at surgery [odds ratio (OR), 1.05; 95% confidence interval (CI), 1.01-1.1] and signifi...Continue Reading

Citations

Jun 1, 2020·International Journal of Colorectal Disease·Jara E JonkerPaul M A Broens
Aug 11, 2020·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·D M BakerA J Lobo
Jan 14, 2021·World Journal of Gastrointestinal Surgery·Tomoaki KitaharaShinichi Okazumi
Apr 2, 2020·Inflammatory Intestinal Diseases·Saki YamadaToshifumi Wakai

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