Long-term radiographic assessment of cemented polyethylene acetabular cups

Clinical Orthopaedics and Related Research
Sophie WilliamsJohn Older

Abstract

In vitro studies demonstrating excessive wear in polyethylene cups sterilized using gamma irradiation and stored in air led to the abandonment of this sterilization technique. We evaluated the clinical wear performance of a metal femoral component on a polyethylene cup in a hip prosthesis from a selected subset of implants in a group of patients followed for at least 20 years and assessed the time dependency of variation in penetration rates. We measured penetration in 33 polyethylene cups in 25 patients who had a Charnley low-friction arthroplasty between 1982 and 1984. All patients had Charnley Ogee cups implanted for more than 20 years and sterilized using the gamma irradiation in air technique. If degradation occurred over time in vivo, it was not reflected by an increased penetration rate with increasing time in vivo; even after 20 years of implantation, the degree of wear remained low. This suggests gamma irradiation affects wear on ultra-high-molecular-weight polyethylene by reducing wear secondary to the crosslinking, by increasing wear as shown through in vitro studies of heavily oxidized samples, or by oxidation resulting from prolonged shelf life. The effect of progressive oxidation in vivo does not appear to affect ...Continue Reading

References

Jan 1, 1996·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·G H IsaacB M Wroblewski
Jan 1, 1995·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·R M HallB M Wroblewski
May 1, 1997·The Journal of Bone and Joint Surgery. American Volume·S M ShaverJ J Callaghan
Apr 8, 1998·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·R M HallB M Wroblewski
Nov 6, 1998·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·R M HallB M Wroblewski
Jul 3, 1999·The Journal of Bone and Joint Surgery. American Volume·C J SychterzC A Engh
Jan 15, 2000·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·P S BarbourJ Fisher
Oct 12, 2004·Biomaterials·Eileen Ingham, John Fisher
Aug 15, 2006·Clinical Orthopaedics and Related Research·Philip M FarisGregory W Faris

❮ Previous
Next ❯

Citations

Apr 1, 2017·Acta Biomaterialia·Giuseppe Pezzotti
Nov 12, 2010·Journal of Biomaterials Science. Polymer Edition·Giuseppe PezzottiNobuhiko Sugano
Mar 14, 2009·Clinical Orthopaedics and Related Research·Philippe HernigouAlexandre Poignard
Feb 20, 2014·Attachment & Human Development·Ashley M GrohGlenn I Roisman
Mar 17, 2020·Journal of Child and Adolescent Mental Health·Renate Gericke, Katherine Bain

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The Journal of Bone and Joint Surgery. British Volume
R J Izquierdo-AvinoB M Wroblewski
Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
G H IsaacB M Wroblewski
Biomedical Materials
Himanshu Bhatt, Tarun Goswami
© 2021 Meta ULC. All rights reserved