Abstract
Myopia has become a big public health problem in certain parts of the world. Sight-threatening complications like choroidal neovascularisation membranes occur in up to 10% of pathological myopia, and natural history studies show a trend towards progressive visual loss. There are long-term financial and quality-of-life implications in this group of patients, and treatment strategies should aim for long-term preservation of vision. A 56-year-old Caucasian woman presented with a best-corrected visual acuity of 6/6-1 in her right eye and 6/24 in her left. Fundal examination revealed pathological myopia in both eyes and an elevated lesion associated with pre-retinal haemorrhage in the left macula. Ocular coherence tomography and fundus fluorescein angiogram confirmed a subfoveal classic choroidal neovascularisation membrane. The patient decided to proceed with intravitreal ranibizumab (0.5 mg) therapy. One month after treatment, best-corrected visual acuity improved to 6/12 in her left eye, with complete resolution subretinal fluid on ocular coherence tomography. After three months, best-corrected visual acuity further improved to 6/9, which was maintained up to 16 months post-treatment. We suggest intravitreal ranibizumab as an alt...Continue Reading
References
Jan 1, 1990·International Ophthalmology Clinics·D S FongR R Allingham
Jun 15, 1989·Biochemical and Biophysical Research Communications·N Ferrara, W J Henzel
Jan 1, 1988·Acta Ophthalmologica. Supplement·E Goldschmidt
Jul 3, 2002·Ophthalmology·M Cristina LeskeUNKNOWN Barbados Eye Studies Group
Oct 16, 2003·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Theodore Grosvenor
Aug 17, 2005·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Seang-Mei SawWei-Han Chua
Jul 28, 2006·The British Journal of Ophthalmology·Izumi YamamotoJay S Duker
Aug 18, 2006·The British Journal of Ophthalmology·H SakaguchiY Tano
Oct 6, 2006·The New England Journal of Medicine·Philip J RosenfeldUNKNOWN MARINA Study Group
Oct 13, 2006·Retina·Napoleone FerraraRobert Kim
Jun 30, 2007·Ophthalmology·Wai-Man ChanDennis S C Lam
Sep 13, 2008·Retina·Rufino M SilvaJosé G Cunha-Vaz
Dec 2, 2008·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Lazaros KonstantinidisAude Ambresin
Dec 19, 2008·The British Journal of Ophthalmology·J M Ruiz-MorenoS Ares
Citations
Aug 19, 2011·Clinical Ophthalmology·Saidin Nor-MasniwatiEmbong Zunaina
Nov 18, 2011·Journal français d'ophtalmologie·G DethoreyH É Souied
Mar 22, 2013·Retina·Erqian Wang, Youxin Chen
Oct 23, 2015·Journal of Ophthalmology·Lyubomyr LytvynchukGoran Petrovski
May 10, 2012·Progress in Retinal and Eye Research·Kumari NeelamTien Y Wong