Long-term reported outcomes of transoral incisionless fundoplication: an 8-year cohort study.

Surgical Endoscopy
Munyaradzi ChimukangaraKyle A Perry

Abstract

Transoral incisionless fundoplication (TIF) offers an endoscopic approach to the treatment of gastroesophageal reflux disease (GERD). Controlled trials have demonstrated the short-term efficacy of this procedure, but long-term follow-up studies are lacking. The objective of this study was to evaluate the long-term impact of TIF on disease-specific quality of life and antisecretory medication use. We performed retrospective cohort study of all patients undergoing TIF between 2007 and 2014 in a large academic medical center. Reflux symptoms and quality of life were assessed using the gastroesophageal reflux disease health-related quality of life (GERD-HRQL) questionnaire at baseline, short-term, and long-term follow-up. Fifty-seven patients with a median age of 46 (37-59) years and an average BMI of 28.8 ± 4.9 kg/m2 underwent TIF during the study period. Sixty percent of the patients were female, and all were taking a PPI at least daily. At a median follow-up interval of 97 months, twelve patients had undergone subsequent laparoscopic antireflux surgery (LARS). Of those who had not, 23 had complete long-term follow-up data for analysis and were included in the study. Seventy-three percent reported daily acid-reducing medication u...Continue Reading

References

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Citations

Feb 28, 2020·Khirurgiia·D A DanilovaL I Gorbunova
Nov 4, 2020·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Kelly R Haisley, Lee L Swanström
Mar 10, 2020·Gastrointestinal Endoscopy Clinics of North America·Kenneth J Chang, Reginald Bell
Feb 28, 2021·Journal of the American College of Surgeons·Kyle A Perry
May 21, 2019·Gastrointestinal Endoscopy·Fateh BazerbachiBarham K Abu Dayyeh
May 6, 2021·Therapeutic Advances in Gastroenterology·Reginald C W BellShahin Ayazi
May 27, 2021·Endoscopy·Pier Alberto TestoniSandro Passaretti
Oct 16, 2021·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Rakesh KalapalaDuvvur Nageshwar Reddy
Feb 3, 2022·Journal of Robotic Surgery·Savni SatoskarVinay Singhal

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