Long-term Results After Surgical or Nonsurgical Treatment in Patients With Degenerative Lumbar Spinal Stenosis: A Prospective Multicenter Study

Spine
Jakob M BurgstallerLSOS Study Group

Abstract

Prospective, multicenter cohort study. The aim of our study was to assess the course of patients over a period of 3 years undergoing surgical or nonsurgical treatments for degenerative lumbar spinal stenoses (DLSS) based on data from the Lumbar Stenosis Outcome Study (LSOS), prospectively performed in eight hospitals. The optimal treatment strategy for patients with DLSS is still debated. The outcomes of patients with verified DLSS were quantified by Spinal Stenosis Measure (SSM) symptoms- and SSM function-scores, and EQ-5D-3L (quality of life) summary index (SI) over time (up to 36-month follow-up), and minimal clinically important difference (MCID) in SSM symptoms, SSM function, and EQ-5D-3L SI from baseline to 36-month follow-up. For this study, 601 patients met the inclusion criteria; 430 underwent surgery, 18 of them only after more than a year after enrolment, 171 received nonsurgical treatment only. At baseline, patients in the surgical and nonsurgical groups had similar values for the SSM symptoms and SSM function scores, but patients in the surgical group suffered significantly more from buttocks pain and reported more worsening symptoms over the last 3 months before enrollment in the study. Surgically treated patients...Continue Reading

References

Mar 16, 2001·Clinical Orthopaedics and Related Research·K K HansrajF J Dorey
Dec 13, 2002·Joint, Bone, Spine : Revue Du Rhumatisme·Michel Benoist
May 28, 2003·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·K-A JanssonG Németh
May 10, 2005·Journal of the American Geriatrics Society·Yuchiao ChangSteven J Atlas
Dec 22, 2005·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Samo K Fokter, Scott A Yerby
Jan 5, 2007·Spine·Antti MalmivaaraUNKNOWN Finnish Lumbar Spinal Research Group
Feb 20, 2007·Clinical Orthopaedics and Related Research·Aravind Athiviraham, David Yen
Feb 22, 2008·The New England Journal of Medicine·James N WeinsteinUNKNOWN SPORT Investigators
Apr 8, 2010·JAMA : the Journal of the American Medical Association·Richard A DeyoJeffrey G Jarvik
Jul 14, 2010·The Spine Journal : Official Journal of the North American Spine Society·Richard A Deyo
Nov 4, 2010·BMC Musculoskeletal Disorders·Johann SteurerUNKNOWN LumbSten Research Collaboration
Jan 18, 2011·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Pär SlätisHeikki Hurri
Jul 9, 2013·The Spine Journal : Official Journal of the North American Spine Society·D Scott KreinerUNKNOWN North American Spine Society
Apr 7, 2015·Annals of Internal Medicine·Anthony DelittoWilliam C Welch
Jan 6, 2016·BMJ : British Medical Journal·Jon Lurie, Christy Tomkins-Lane
Apr 14, 2016·The New England Journal of Medicine·Peter FörsthBengt Sandén
Apr 14, 2016·The New England Journal of Medicine·Zoher GhogawalaEdward C Benzel

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