Long-term results after surgical treatment of paravalvular leak in the aortic and mitral position

The Journal of Thoracic and Cardiovascular Surgery
Ismail BouhoutDenis Bouchard

Abstract

The aim of this study was to determine immediate results and long-term outcomes after surgical management of paravalvular leak (PVL). Between 1995 and 2012, a total of 190 patients underwent primary surgical repair (n = 142) or valve replacement (n = 48) for a PVL at our institution. The PVL was mild in 6 (3%) patients, moderate in 85 (45%), moderate to severe in 84 (44%), and severe in 15 (8%). Among these, 120 (63%) had PVL in the mitral position, 63 (33%) had PVL in the aortic position, and 7 (4%) had PVL in both valves. Mean follow-up was 5.3 ± 4.6 years. Mean age at surgery was 63 ± 12 years (64% men). Operative mortality occurred in 13 (7%) patients (10 [8%] in mitral; 2 [3%] in aortic; and 1 [14%] in double valve procedures). Survival at 1, 5, and 10 years was 85% ± 3%, 73% ± 4%, and 56% ± 5%, respectively. The cumulative incidence of PVL recurrence was 3% ± 1%, 14% ± 3%, and 32% ± 6%, at 1, 5, and 10 years, respectively. The number of previous surgeries was a predictor of survival and PVL recurrence. Freedom from New York Heart Association class ≥III was 96% ± 2%, 82% ± 4%, and 58% ± 6%, at 1, 5, and 10 years, respectively. The freedom from rehospitalization for heart failure was 92% ± 2%, 83% ± 4%, and 67% ± 6%, at 1, ...Continue Reading

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Citations

Jan 27, 2016·The Journal of Thoracic and Cardiovascular Surgery·Mathew R WilliamsEugene A Grossi
Oct 19, 2016·The Journal of Thoracic and Cardiovascular Surgery·David W YaffeeEugene A Grossi
Mar 8, 2018·Current Cardiology Reports·Kashish Goel, Mackram F Eleid
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May 30, 2019·The Journal of Cardiovascular Surgery·Yoshiaki KatadaTomoki Shimokawa
Apr 27, 2017·Interactive Cardiovascular and Thoracic Surgery·Luca BottaClaudio Francesco Russo
Oct 20, 2017·Interactive Cardiovascular and Thoracic Surgery·Sameh M SaidJoseph A Dearani
Sep 19, 2020·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Shin YajimaTomoyuki Fujita
Aug 23, 2019·Revista do Colégio Brasileiro de Cirurgiões·José Dantas de Lima JúniorHenrique Jorge Stahlke Júnior
Oct 11, 2020·Current Cardiology Reports·Elias J FanousAsim M Rafique
Mar 23, 2021·Journal of Interventional Cardiology·Yang LiuJian Yang
Mar 17, 2021·Revista Portuguesa De Cardiologia : Orgão Oficial Da Sociedade Portuguesa De Cardiologia = Portuguese Journal of Cardiology : an Official Journal of the Portuguese Society of Cardiology·Ana Pardo Sanz, José Luis Zamorano
Nov 12, 2018·The Journal of Thoracic and Cardiovascular Surgery·Shailee ShahMilind Y Desai
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Jul 6, 2021·European Heart Journal. Case Reports·Igor Vyacheslavovich BuzaevEustaquio Maria Onorato
Jul 17, 2021·Current Cardiology Reports·Aken DesaiJohn Carroll
Nov 26, 2021·Journal of Cardiac Surgery·Imran Karim JanmohamedAmer Harky

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