Long term results and predictors of left ventricular function recovery after aortic valve replacement for chronic aortic regurgitation

Annals of Thoracic and Cardiovascular Surgery : Official Journal of the Association of Thoracic and Cardiovascular Surgeons of Asia
Hiroyuki SaishoHiroyuki Tanaka

Abstract

In most patients with aortic regurgitation (AR), aortic valve replacement (AVR) improves left ventricular (LV) function, but some patients will not have favorable remodeling. Our objectives were to review long term clinical results of AVR for AR and to examine what factors affect the normalization of LV function after AVR for chronic AR. Between 1989 and 2010, 177 patients underwent isolated AVR for chronic pure AR. The patients were divided into 2 groups based on indexed end-systolic LV diameter (iESD): Group L (iESD) ≥25 mm/m(2)) (130 patients) and Group S (iESD <25 mm/m(2)) (47 patients). There was no significant difference between groups in late mortality, freedom from cardiac-related death and rehospitalization for heart failure at late follow up after operation. At postoperative follow-up, 16% of patients had not recovered normal LV systolic function. By means of multivariate analysis, iESD and cardiac index (CI) were independent predictors of recovery of LV function and iESD >26.7 mm/m(2) and CI <2.71 l/min/m(2) were the best cut-off values. Early and late surgical results of AVR for chronic AR were good, but for the preservation of postoperative normal LV function, AVR for AR patients should be performed before iESD rea...Continue Reading

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Citations

Apr 2, 2019·European Heart Journal Cardiovascular Imaging·E Mara VollemaVictoria Delgado
Mar 23, 2017·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Yin WangNianguo Dong
Sep 15, 2020·Circulation Journal : Official Journal of the Japanese Circulation Society·Chisato IzumiUNKNOWN Japanese Circulation Society Joint Working Group
Aug 31, 2021·Circulation Journal : Official Journal of the Japanese Circulation Society·Masashi Amano, Chisato Izumi

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