Long term results in the management of craniopharyngiomas

Neurosurgery
F G McMurryW J Gardner

Abstract

The results of surgical treatment, with and without radiotherapy, in 50 patients with craniopharyngioma treated over a 26-year period at the Cleveland Clinic are presented. Thirty-five patients were operated upon before the introduction of the operating microscope, and 30 of these survived operation. In this group of 30 patients, long term survival (5 to 24 years) occurred in 8 of 10 (80%) nonradiated patients who were considered to have had total excision. Nine of 11 patients (82%) who had aggressive subtotal excision and radiation therapy have survived from 3 to 17 years. Seven of nine patients (78%) died 1 to 14 years after subtotal excision without radiation therapy. Since the introduction of the operating microscope in 1972, 15 patients have had surgical treatment, and 12 of these have survived.

Citations

Aug 1, 1984·European Journal of Pediatrics·N StahnkeR P Willig
Oct 24, 2012·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Aaron J ClarkNalin Gupta
Jun 11, 2010·Journal of Neuro-oncology·Michael E SughrueAndrew T Parsa
Nov 7, 1998·International Journal of Radiation Oncology, Biology, Physics·Y KhafagaA Gray
Jul 10, 2003·Pediatric Neurology·Sharon L TowAnthony M Avellino
Jan 1, 1995·Acta neurochirurgica·D PrasadL Steiner
Sep 30, 1993·International Journal of Radiation Oncology, Biology, Physics·M Brada, D G Thomas
Jan 1, 1989·International Journal of Radiation Oncology, Biology, Physics·B C WenJ F Doornbos
Dec 19, 2013·Surgical Neurology International·Gazanfar Rahmathulla, Gene H Barnett
Jul 1, 1982·AORN Journal·S Heyman
Jan 1, 1986·Acta neurochirurgica·R Sorva, O Heiskanen

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