Long-term Results of a Randomized Double-blinded Prospective Trial of a Lightweight (Ultrapro) Versus a Heavyweight Mesh (Prolene) in Laparoscopic Total Extraperitoneal Inguinal Hernia Repair (TULP-trial)

Annals of Surgery
J P J BurgmansThijs van Dalen

Abstract

The aim of the randomized clinical trial was to compare the 2 years of clinical outcomes of a lightweight (Ultrapro) vs a heavyweight (Prolene) mesh for laparoscopic total extraperitoneal (TEP) inguinal hernia repair. Lightweight meshes reduce postoperative pain and stiffness in open anterior inguinal hernia repair. The discussion about a similar benefit for laparoscopic repair is ongoing, but concerns exist about higher recurrence rates. Between March 2010 and October 2012, male patients who presented with a primary, reducible unilateral inguinal hernia who underwent day-case TEP repair were eligible. Outcome parameters included chronic pain, recurrence, foreign body feeling, and quality of life scores. During the study period, 950 patients were included. One year postoperatively the presence of relevant pain (Numeric Rating Score 4-10) was significantly higher in the lightweight mesh group (2.9%) compared with the heavyweight mesh group (0.7%) (P = 0.01), and after 2 years this difference remained significant (P = 0.03). There were 4 (0.8%) recurrent hernias in the heavyweight mesh group and 13 (2.7%) in the lightweight group (P = 0.03). No differences in foreign body feeling or quality of life scores were detected. In TEP he...Continue Reading

References

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Citations

Mar 14, 2017·Annals of Surgery·Claudio BrandiEugenia Fratantoni
Feb 1, 2018·Hernia : the Journal of Hernias and Abdominal Wall Surgery·M M RoosJ P J Burgmans
Sep 21, 2017·Praxis·Joël L LavanchyGuido Beldi
Dec 21, 2017·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Cory N CrissSamir K Gadepalli
Jan 18, 2019·Hernia : the Journal of Hernias and Abdominal Wall Surgery·W J BakkerJ P J Burgmans
Sep 5, 2019·Hernia : the Journal of Hernias and Abdominal Wall Surgery·C V van HessenJ P J Burgmans
Nov 16, 2016·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Dimitrios PrassasFranz-Josef Schumacher
Aug 24, 2018·Plastic and Reconstructive Surgery·Clayton C Petro, Michael J Rosen
Feb 20, 2019·Hernia : the Journal of Hernias and Abdominal Wall Surgery·W J BakkerJ P J Burgmans
May 8, 2019·Hernia : the Journal of Hernias and Abdominal Wall Surgery·F Köckerling
Sep 24, 2018·Hernia : the Journal of Hernias and Abdominal Wall Surgery·M M RoosJ P J Burgmans
Mar 14, 2020·Hernia : the Journal of Hernias and Abdominal Wall Surgery·E ÖzveriM Ertem
May 12, 2017·Innovative Surgical Sciences·Wolfgang Reinpold
Apr 6, 2021·Journal of Surgical Case Reports·Ivana RaguzAndreas Thalheimer
Sep 5, 2021·Hernia : the Journal of Hernias and Abdominal Wall Surgery·A Gram-HanssenJ Rosenberg
Sep 24, 2021·ANZ Journal of Surgery·James O'BrienRichard Turner

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