Long-term results of accelerated and conventional corneal cross-linking.

International Ophthalmology
Samara Barbara MarafonDiane Ruschel Marinho

Abstract

The aim of this study is to compare the long-term follow-up outcomes of traditional and accelerated corneal cross-linking (CXL) for keratoconus. This retrospective comparative cohort study included patients with keratoconus who underwent corneal cross-linking (CXL) between August 2008 and December 2016. Patients treated before August 2013 underwent the traditional Dresden protocol, and those treated subsequently received the accelerated protocol, i.e., 0.1% riboflavin soaking for 10 min, followed by pulsed UV-A irradiation at 30 mW/cm2 for 8 min, and a total irradiation power of 7.2 J/cm2. The primary outcome was the success rate in halting the disease progression. The postoperative changes in visual acuity, keratometry readings, endothelial cell count and complications following accelerated CXL and conventional CXL were compared. This study evaluated 113 eyes over a mean follow-up period of 37.61 ± 16.34 months. It was found that 89.6% and 95.7% of the eyes were successfully treated with the traditional and accelerated protocols, respectively (p = 0.239). The corrected-distance visual acuity improved in both groups, but it was significantly better following the accelerated protocol (p = 0.037). Traditional protocol group had m...Continue Reading

References

Jan 1, 1984·Survey of Ophthalmology·J H KrachmerM W Belin
Oct 1, 1980·Experimental Eye Research·T T AndreassenH Oxlund
Mar 11, 1998·Survey of Ophthalmology·Y S Rabinowitz
Sep 27, 2001·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·A SchindlF Trautinger
Apr 30, 2003·American Journal of Ophthalmology·Gregor WollensakTheo Seiler
Mar 3, 2009·Journal of Cataract and Refractive Surgery·Matthias Pollhammer, Claus Cursiefen
Jul 28, 2009·Journal of Cataract and Refractive Surgery·Tobias KollerTheo Seiler
Sep 24, 2009·Journal of Refractive Surgery·Frederik RaiskupEberhard Spoerl
Oct 14, 2009·Archives of Ophthalmology·Paolo VinciguerraDaniel Epstein
May 8, 2010·Clinical & Experimental Ophthalmology·Rita MencucciGabriella B Vannelli
Jun 10, 2011·Klinische Monatsblätter für Augenheilkunde·D KampikG Geerling
Aug 13, 2011·Journal of Ophthalmology·Aldo CaporossiRosario Denaro
Oct 26, 2011·Investigative Ophthalmology & Visual Science·Silvia SchumacherMichael Mrochen
Nov 23, 2011·Journal of Cataract and Refractive Surgery·Massimo FilippelloDavid O'Brart
Jan 10, 2013·Investigative Ophthalmology & Visual Science·Jeremy WernliMichael Mrochen
Jul 31, 2013·Journal of Cataract and Refractive Surgery·Steven A Greenstein, Peter S Hersh
May 27, 2014·Journal of Cataract and Refractive Surgery·Minoru TomitaTukezban Huseynova
Jul 19, 2014·American Journal of Ophthalmology·George D KymionisMiltiadis K Tsilimbaris
Mar 26, 2015·Journal of Cataract and Refractive Surgery·Hassan HashemiSoheila Asgari
Jul 4, 2015·Clinical & Experimental Ophthalmology·Alex Lap Ki NgArthur Ck Cheng
Jun 16, 2016·Journal of Refractive Surgery·Marcony R Santhiago
Nov 15, 2016·Journal of Cataract and Refractive Surgery·Mustafa KocPelin Yilmazbas
Dec 23, 2016·Journal of Cataract and Refractive Surgery·Carla S MedeirosMarcony R Santhiago
Dec 24, 2016·European Journal of Ophthalmology·David P S O'Brart
Jun 9, 2017·Current Opinion in Ophthalmology·George D KymionisKattayoon K Hashemi
Nov 11, 2019·Journal of Cataract and Refractive Surgery·Kenneth A BeckmanUNKNOWN ASCRS Cornea Clinical Committee

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Citations

Dec 17, 2020·Asia-Pacific Journal of Ophthalmology·Colin Chan
Dec 8, 2021·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·Louisa M BulirschMartina C Herwig-Carl

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