Long-term results of intravitreal bevacizumab and dexamethasone for the treatment of punctate inner choroidopathy associated with choroidal neovascularization: A case series

SAGE Open Medical Case Reports
Konstantinos T TsaousisTheo Empeslidis

Abstract

To present a case series of three female patients with punctate inner choroidopathy. We report the outcomes after an essentially long follow-up period of up to 14 years and provide evidence of the effectiveness of intravitreal injections of bevacizumab and dexamethasone 0.7 mg in punctate inner choroidopathy patients with choroidal neovascular membrane formation. This is a retrospective case series of three female patients with punctate inner choroidopathy who were treated with intravitreal injections anti-vascular endothelial growth factor agent (bevacizumab, 1.25 mg/0.05 mL). Two patients also received intravitreal dexamethasone 0.7 mg. Once a choroidal neovascular membrane developed, the outcome was poor with a best-corrected visual acuity of 6/60 or counting fingers in the affected eyes. The patients were followed up for 5, 14 and 8 years. The use of dexamethasone 0.7 mg in punctate inner choroidopathy yielded encouraging results and long periods of stability. When choroidal neovascular membrane complicates the primary disease, the prognosis is unfavourable, especially if the macula integrity has already been considerably affected. On the contrary, aggressive early therapy and continued monthly monitoring can prevent severe...Continue Reading

References

Nov 1, 1984·American Journal of Ophthalmology·R C WatzkeR R Ober
Mar 12, 2004·American Journal of Ophthalmology·David A QuillenRobert A Equi
Apr 17, 2007·Ophthalmology·Adam T GerstenblithQuan Dong Nguyen
Apr 17, 2008·Clinical & Experimental Ophthalmology·Urs VossmerbaeumerJost B Jonas
Jul 23, 2015·Annals of the New York Academy of Sciences·Scott M Whitcup, Michael R Robinson
Oct 13, 2016·Therapeutics and Clinical Risk Management·Barbara Terelak-BorysIwona Grabska-Liberek
Oct 19, 2016·Survey of Ophthalmology·Dana AhnoodAlastair K Denniston
Mar 24, 2017·International Journal of Retina and Vitreous·Meisha L RavenJustin L Gottlieb

❮ Previous
Next ❯

Related Concepts

Related Feeds

Arterial-Venous in Development & Disease

Arterial-venous development may play a crucial role in cardiovascular diseases. Here is the latest research.

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.