Abstract
To evaluate the feasibility of mitral valve repair in patients with anterior leaflet (ALP) or bileaflet prolapse (BLP) and identify factors predisposing patients to replacement. To compare long-term survival of patients submitted to repair (Group Repair) against those submitted to replacement (Group Replacement), and investigate causes of early and late failures of repair. From January 1992 through December 2012, 768 patients with ALP or BLP were submitted to mitral valve surgery, of whom 501 had degenerative involvement [Myxomatous (Myx)-336 (67.1%) or fibroelastic deficiency (Fed)-165 (32.9%)] and constituted the study population. Isolated ALP was present in 274 patients (54.7%) and BLP in 227 (45.3%). Associated procedures were admitted. Patients with Fed were significantly older (64.4 ± 12.1 vs 54.8 ± 15.5 years, P < 0.001), more symptomatic (63 vs 44.3%; P < 0.001) and with higher incidence of atrial fibrillation (43.6 vs 26.2%; P < 0.001). Repair was achieved in 94.8% of patients with an overall 30-day mortality rate of 1.2% (0.3% in the last decade) and no differences regarding aetiology. Age, moderate to severe left ventricular (LV) dysfunction, previous cardiac surgery, multiple segment prolapse, mitral calcification, ...Continue Reading
References
Nov 7, 1998·The Journal of Thoracic and Cardiovascular Surgery·A M GillinovF D Loop
Jan 26, 1999·Circulation·C M TribouilloyR L Frye
Jul 4, 2001·Circulation·R D McBaneW W Bate
Oct 2, 2003·Journal of the National Cancer Institute·Dianne M FinkelsteinDavid A Schoenfeld
Nov 1, 2005·The Journal of Thoracic and Cardiovascular Surgery·Tirone E DavidHarry Rakowski
Feb 7, 2006·European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology·Roberto M LangUNKNOWN European Association of Echocardiography, European Society of Cardiology
Feb 21, 2006·The Annals of Thoracic Surgery·Gerald M LawrieNan R Earle
Aug 25, 2006·The Annals of Thoracic Surgery·Rakesh M SuriThomas A Orszulak
Jul 24, 2007·The Annals of Thoracic Surgery·Eric DumontBruce W Lytle
Feb 5, 2008·The Journal of Thoracic and Cardiovascular Surgery·Willem FlamengMarie-Christine Herregods
Mar 4, 2008·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Cary W AkinsBruce W Lytle
Aug 30, 2008·The Annals of Thoracic Surgery·A Marc GillinovBruce W Lytle
Sep 23, 2008·The Journal of Thoracic and Cardiovascular Surgery·David H Adams, Ani C Anyanwu
Nov 26, 2009·The Annals of Thoracic Surgery·Mani A DaneshmandDonald D Glower
Apr 27, 2010·The Annals of Thoracic Surgery·Douglas R JohnstonBruce W Lytle
Mar 26, 2011·The Annals of Thoracic Surgery·Tomoki ShimokawaShuichiro Takanashi
Dec 16, 2011·The Journal of Thoracic and Cardiovascular Surgery·Yukikatsu OkadaYasunobu Konishi
Jun 16, 2012·The Journal of Thoracic and Cardiovascular Surgery·Javier G CastilloDavid H Adams
Mar 6, 2013·Circulation·Tirone E DavidCedric Manlhiot
Apr 30, 2013·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Javier G CastilloDavid H Adams
Mar 5, 2014·Circulation·Rick A NishimuraJames D Thomas
Mar 8, 2014·Journal of the American College of Cardiology·Rick A NishimuraJames D Thomas
Aug 26, 2014·The Journal of Thoracic and Cardiovascular Surgery·Gonçalo F CoutinhoManuel J Antunes
Dec 3, 2014·The Journal of Thoracic and Cardiovascular Surgery·Manuel J Antunes, Gonçalo F Coutinho
Citations
Jun 2, 2017·Heart·Gonçalo F Coutinho, Manuel J Antunes
Oct 30, 2018·International Heart Journal·Ying GuoXiaohong Huang
Feb 23, 2018·Innovations : Technology and Techniques in Cardiothoracic and Vascular Surgery·Olivia K GintyMichael W A Chu
Sep 5, 2019·Expert Review of Cardiovascular Therapy·Francesca MantovaniAndrea Barbieri
Jan 12, 2019·A&A Practice·Zhifeng GaoKamal R Khabbaz
Sep 24, 2019·The Thoracic and Cardiovascular Surgeon·Konstantinos SiderisRalf Guenzinger
Jul 11, 2020·Current Cardiology Reports·P OvertchoukT Modine
Apr 12, 2017·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Torsten DoenstGloria Faerber
May 26, 2018·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Gonçalo F CoutinhoManuel J Antunes
Apr 20, 2019·Journal of Clinical Medicine·Simone GasserEvaldas Girdauskas
Jul 1, 2020·Nature Reviews. Cardiology·Benedetto Del FornoOttavio Alfieri
Jun 1, 2019·A&A Practice·Zhifeng GaoKamal R Khabbaz
Jan 9, 2020·BMC Cardiovascular Disorders·Pavel OvertchoukThomas Modine
Nov 30, 2019·Journal of Cardiothoracic Surgery·Daisuke KaneyukiAtsushi Iguchi
Jun 17, 2019·JACC. Cardiovascular Imaging·Yasmine L HiemstraNina Ajmone Marsan
Sep 30, 2018·The Journal of Thoracic and Cardiovascular Surgery·Torsten Doenst
Jun 5, 2019·A&A Practice·Zhifeng GaoKamal R Khabbaz
Mar 23, 2021·Revista Portuguesa De Cardiologia : Orgão Oficial Da Sociedade Portuguesa De Cardiologia = Portuguese Journal of Cardiology : an Official Journal of the Portuguese Society of Cardiology·Gonçalo F Coutinho, Manuel J Antunes
Apr 20, 2021·Heart, Lung & Circulation·Haruka SasakiYoshio Kobayashi
Apr 26, 2021·Cardiology Clinics·Benedetto Del FornoMichele De Bonis
Apr 19, 2021·Seminars in Thoracic and Cardiovascular Surgery·Alexander A BresciaMatthew A Romano
Jun 17, 2021·Journal of Cardiothoracic Surgery·Qianqian FanFengxiao Zhang
Apr 20, 2020·The Journal of Thoracic and Cardiovascular Surgery·Alexander A BresciaUNKNOWN Michigan Mitral Research Group