PMID: 8460150Mar 15, 1993Paper

Long-term retention of learning-induced receptive-field plasticity in the auditory cortex

Proceedings of the National Academy of Sciences of the United States of America
N M WeinbergerB Lepan

Abstract

Brief learning experience (classical conditioning) induces frequency-specific receptive-field (RF) plasticity in the auditory cortex, characterized as increased response to the frequency of the conditioned stimulus and decreased responses to most other frequencies, including the pretraining best frequency. This experiment asked (i) whether learning-induced RF plasticity, established in the waking state, can be expressed under general anesthesia and if so (ii) whether it exhibits long-term retention. Pure-tone-frequency RFs were obtained from adult guinea pigs under general anesthesia (sodium pentobarbital or ketamine) before and repeatedly after (1 hr-8 weeks) a 20- to 30-trial session of pairing a non-best-frequency tone with mild footshock. Conditioned-stimulus-specific RF plasticity was expressed under both types of anesthesia and included shifts of the pretraining best frequency toward or even to the frequency of the conditioned stimulus. Moreover, this RF plasticity exhibits long-term retention, being evident 1-8 weeks after training. This satisfies a criterion for the long-term storage of information in the auditory cortex.

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Citations

Feb 2, 2013·Cognitive Neurodynamics·Yoshinori IdeTakeshi Aihara
Apr 25, 1994·Neuroscience Letters·M Kudoh, K Shibuki
Aug 1, 1993·Current Opinion in Neurobiology·N M Weinberger
Aug 1, 1994·Current Opinion in Neurobiology·E Ahissar, M Ahissar
Apr 1, 1995·Current Opinion in Neurobiology·S L MillerP Tallal
Jun 19, 1998·Brain Research·B V Chernyshev, N M Weinberger
Sep 23, 2000·Journal of Communication Disorders·D R Irvine
Oct 1, 1996·Brain Research. Brain Research Reviews·S J Cruikshank, N M Weinberger
Mar 29, 2003·Neural Networks : the Official Journal of the International Neural Network Society·Paul F.M.J. Verschure, Thomas Voegtlin
Mar 23, 2004·Nature Reviews. Neuroscience·Norman M Weinberger
Jun 14, 2001·The European Journal of Neuroscience·M A Kisley, G L Gerstein
Feb 29, 2008·Proceedings of the National Academy of Sciences of the United States of America·Riccardo Accolla, Alan Carleton
Feb 6, 2010·Proceedings of the National Academy of Sciences of the United States of America·Kasia M Bieszczad, Norman M Weinberger
Oct 1, 1996·Proceedings of the National Academy of Sciences of the United States of America·J S Bakin, N M Weinberger
Apr 1, 2004·Learning & Memory·Julie Marie GottseligPeter Achermann
Jan 28, 2005·The European Journal of Neuroscience·Jun Yan, Yunfeng Zhang
Jan 1, 1995·Annual Review of Neuroscience·N M Weinberger
Apr 8, 1998·Annual Review of Neuroscience·D V Buonomano, M M Merzenich
May 7, 2010·Journal of Neurophysiology·Michael C WiestMiguel A L Nicolelis
Aug 22, 2012·Journal of Cognitive Neuroscience·Jihoon OhJaeseung Jeong
May 9, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Michael J MillerAlice M Wyrwicz
Oct 15, 1998·Proceedings of the National Academy of Sciences of the United States of America·E Gao, N Suga
Aug 28, 2003·Proceedings of the National Academy of Sciences of the United States of America·Ralph E BeitelMichael M Merzenich
Jul 8, 2000·Proceedings of the National Academy of Sciences of the United States of America·E Gao, N Suga
Nov 7, 2002·Proceedings of the National Academy of Sciences of the United States of America·Zhongju Xiao, Nobuo Suga
Nov 3, 2005·Psychological Review·Alexander A PetrovZhong-Lin Lu
Feb 10, 2016·Frontiers in Behavioral Neuroscience·Hisayuki Ojima, Junsei Horikawa
Sep 28, 2010·Neurobiology of Learning and Memory·Zhong-Lin LuBarbara Anne Dosher
May 4, 2010·Neurobiology of Learning and Memory·Kasia M Bieszczad, Norman M Weinberger
Oct 27, 2009·Neurobiology of Learning and Memory·Kasia M Bieszczad, Norman M Weinberger
Nov 26, 2008·Neurobiology of Learning and Memory·Candice M ChavezNorman M Weinberger
Jul 17, 2012·Neuron·Amos GdalyahuJoshua T Trachtenberg
Aug 21, 2007·Neurobiology of Learning and Memory·Kasia M Berlau, Norman M Weinberger
Sep 24, 2005·The European Journal of Neuroscience·W C ClappT J Teyler

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