Long-term safety and efficacy of slow pathway ablation in patients with atrioventricular nodal re-entrant tachycardia and pre-existing prolonged PR interval

Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology
Jean Luc PasquiéRobert Grolleau-Raoux

Abstract

The association of atrioventricular nodal re-entrant tachycardia (AVNRT) and pre-existing prolonged PR interval is unusual. Radiofrequency (RF) ablation in such patients may be associated with an increased risk of immediate and delayed AV block. The aim of our study is to assess the long-term efficacy and safety of slow pathway ablation in this population. We studied 10 patients (4 males and 6 females) with pre-existing prolonged PR interval of 68 consecutive patients with AVNRT. All had slow-fast subtype of AVNRT. The mean PR interval was 222 +/- 15 ms before RF. The patients with pre-existing prolonged PR were older (69 +/- 15 vs. 54 +/- 17, P = 0.008) and their tachycardias were slower (387 +/- 102 vs. 323 +/- 73 ms; P < 0.05). Transient complete AV block (<5 s) occurred in two patients. None had permanent complete AV block. One patient had a significant increase in PR interval (from 220 to 320 ms). The mean post-RF PR interval was 232+/-37 ms (P = n.s.). Over a mean follow-up of 39 +/- 21 months, none had a recurrence of tachycardia nor developed higher degree AV block. In conclusion, in patients with AVNRT and pre-existing prolonged PR interval, a slow pathway ablation appeared efficient and safe. From our data, no delayed...Continue Reading

References

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Citations

Dec 18, 2007·Herzschrittmachertherapie & Elektrophysiologie·C ReithmannG Steinbeck
Dec 17, 2008·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Agustín BortoneJean-Paul Albenque
Apr 7, 2010·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Michal J KantochReeni N Soni
Jul 10, 2013·Future Cardiology·Evaldas Giedrimas, Jeffrey J Goldberger
Feb 20, 2014·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Christopher Reithmann, Michael Fiek
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Oct 5, 2010·Pacing and Clinical Electrophysiology : PACE·Nick W F LintonDavid Lefroy
Apr 5, 2017·Current Treatment Options in Cardiovascular Medicine·Darpan S KumarCharles A Henrikson
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