Long-Term Safety and Longevity of a Mixture of Polymethyl Methacrylate and Cross-Linked Dextran (Lipen-10®) after Penile Augmentation: Extension Study from Six to 18 Months of Follow-Up

The World Journal of Men's Health
Ma Tae KimDae Yul Yang

Abstract

The goal of this study was to investigate the long-term efficacy and safety of a mixture of polymethyl methacrylate (PMMA) and cross-linked dextran Lipen-10® used for penile augmentation under the physical impact generated during sexual intercourse. From March 2010 to October 2011, a total of 20 patients with a mean age of 44 years (interquartile range, 20~70 years) who requested penile augmentation participated in this study. Lipen-10® filler is a mixture of 75% cross-linked dextran, 15% PMMA, and 10% hypromellose solution. With the patient in the supine position, Lipen-10® was injected into the subcutaneous tissue between the dartos fascia and Buck's fascia of the penis using a fanning technique. Penile length and circumference were measured before the procedure and six, 12, and 18 months after the procedure. Values were compared using the Student's t-test and the paired t-test. A total of 15 patients completed this study. The increases in circumference and length observed six months after the procedure were found to have been maintained without change at 12 and 18 months of follow-up. At 12 and 18 months of follow-up, no abnormal findings were observed. Pelvic magnetic resonance imaging conducted at 18 months of follow-up sh...Continue Reading

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Citations

May 13, 2017·Aesthetic Surgery Journal·Jayson Oates, Gemma Sharp
May 11, 2018·Investigative and Clinical Urology·Sang Woon KimSang Won Han
Nov 28, 2018·International Journal of Impotence Research·Sun Tae AhnDu Geon Moon
Nov 3, 2020·Plastic and Reconstructive Surgery·Krishna S VyasOscar Manrique
Feb 16, 2021·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Antoine SalloumRoger Haber
Mar 24, 2021·International Journal of Impotence Research·Daphné VanderhaegheEmmanuel Weyne
May 29, 2021·International Journal of Impotence Research·Nicolò SchifanoGiulio Garaffa
Jul 15, 2021·International Journal of Impotence Research·Celeste ManfrediRados Djinovic

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