Long-term success in the treatment of diffuse pigmented villonodular synovitis of the knee with subtotal synovectomy and radiotherapy

Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association
Lúcio Honório de CarvalhoOtávio de Melo Silva

Abstract

The objective of this study was to evaluate the effectiveness and long-term outcome of the treatment of patients with diffuse pigmented villonodular synovitis (PVNS) of the knee with subtotal arthroscopic and open synovectomy and subsequent external-beam radiotherapy. Eight patients diagnosed with diffuse PVNS by clinical and magnetic resonance imaging were treated surgically with subtotal arthroscopic synovectomy and an additional posterior incision for extra-articular lesions, followed by local adjuvant radiotherapy. These patients were followed up for a mean of 8.6 years to monitor remaining lesions and to detect new occurrences of the condition. None of the patients presented with major postoperative complications or have had radiotherapeutic late effects. In no case was radiographic arthritis progression detected. Three patients exhibited late minor complications (peripatellar pain, articular effusion, and persistent quadricipital muscle atrophy). Only 1 patient (12.5%) presented with recurrence of the disease during the follow-up period. On the basis of our limited study, subtotal arthroscopic and open synovectomy with subsequent local external-beam radiotherapy had a recurrence rate of 12.5% at 8.6 years of follow-up for...Continue Reading

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Citations

Jul 8, 2014·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·Jean-Charles AuréganPhilippe Hardy
Jan 30, 2014·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Hai-Feng GuQing Bi
Oct 14, 2014·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Brent MollonJohn Theodoropoulos
Aug 11, 2016·JBJS Reviews·Stephen R StephanMary K Mulcahey
Apr 22, 2017·Orthopaedics & Traumatology, Surgery & Research : OTSR·T NoaillesF Gouin
Jul 19, 2019·The Journal of Bone and Joint Surgery. American Volume·M J L MastboomUNKNOWN Tenosynovial Giant Cell Tumors (TGCT) Study Group
Jan 1, 2015·Journal of Orthopaedic Surgery·E Carlos Rodriguez-Merchan
Sep 9, 2017·Revista Brasileira De Ortopedia·Eduardo Frois TemponiLúcio Honório de Carvalho Júnior

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